Colorectal Cancer
Adagrasib plus cetuximab receives accelerated approval to treat advanced colorectal cancer
The FDA granted accelerated approval adagrasib with cetuximab for the treatment of KRASG12C -mutated locally advanced or metastatic colorectal cancer, according to a press release from the agency.
Highlights from ASCO Annual Meeting 2024
In this episode of Meeting Mic, we bring you pearls and perspectives from the 2024 ASCO Annual Meeting, as well as Healio’s top headlines from the meeting.
A 100% response rate suggests dostarlimab is ‘definitive’ therapy for rectal cancer
CHICAGO — A phase 2 study evaluating dostarlimab in adults with mismatch repair-deficient locally advanced rectal cancer has maintained a 100% clinical complete response rate at a median follow-up of almost 18 months.
Socially vulnerable neighborhoods linked to increased risk for death after cancer surgery
Individuals who ranked highest on a scale measuring social vulnerability by location had a poorer prognosis following colorectal resection, according to a presentation at Southern Surgical Association Annual Meeting.
FDA panel backs Guardant’s colorectal cancer blood test for favorable risk-benefit
An FDA advisory committee has voted strongly in favor of approval for Guardant Health’s blood test for colorectal cancer, intended for patients aged 45 years and older at average risk for disease.
Many childhood cancer survivors do not undergo recommended tests for late effects
Most childhood cancer survivors are not up to date on guideline-recommended screening for late effects of cancer treatment or second malignancies, according to study results.
Blood-based screening test detects CRC with nearly 80% sensitivity in average-risk adults
WASHINGTON — A blood-based screening test detected colorectal cancer with a sensitivity of 79.2% and a specificity of 91.5% among average-risk adults aged 45 to 85 years, according to research presented at Digestive Disease Week.
‘No convincing evidence’ linking adult oral antibiotic use, early-onset colorectal cancer
WASHINGTON — Oral antibiotic use among adult patients was not associated with increased risk for early-onset colorectal cancer, according to data presented at Digestive Disease Week.
‘Provider recommendation critical’ to colonoscopy uptake for non-Hispanic Black adults
WASHINGTON — Provider recommendation was a major influencer for colonoscopy screening for young adults at average risk for colorectal cancer, especially non-Hispanic Black patients, according to data presented at Digestive Disease Week.
Post-polypectomy surveillance colonoscopy associated with 77% reduction in CRC risk
WASHINGTON — Surveillance colonoscopy after polyp removal was associated with a 77% relative reduction in risk for colorectal cancer, although more research is needed to determine its effect on mortality risk, according to study results.