Colorectal Cancer

The FDA granted priority review to tucatinib in combination with trastuzumab for treatment of certain adults with colorectal cancer.

Two cycles of neoadjuvant nivolumab plus low-dose ipilimumab induced durable pathologic responses among patients with mismatch repair-deficient colon cancer, according to study results presented at ESMO Congress.

Adagrasib alone and in combination with cetuximab exhibited promising efficacy compared with historical outcomes among heavily pretreated patients with advanced colorectal cancer who had KRASG12C mutations.

In men, high consumption of ultra-processed foods was associated with an increased risk for colorectal cancer; however, this association was not found in women, according to study results.

Data showed that colorectal cancer screening delays of 1 to 2 years because of the COVID-19 pandemic had minimal impact on individuals aged 50 to 60 years, whereas these delays had pronounced impact on those aged 65 years and older.

Patients with familial adenomatous polyposis with ileal pouch-anal anastomosis developed ileal adenomas more often than patients with end ileostomy after proctocolectomy, according to research published in Gastrointestinal Endoscopy.

Electronic noses that detect volatile organic compounds in exhaled breath have emerged as potential tools for cancer detection, but more investigation is needed before they can become part of the diagnostic workup, according to researchers.

Loïc Le Marchand, MD, PhD, MPH, has been awarded the 2022 AACR Distinguished Lectureship on the Science of Cancer Health Disparities.

High overall consumption of ultra-processed food appeared associated with a higher risk for colorectal cancer among men, but not women, according to study results published in The BMJ.

Regardless of patient sex or BMI, initiating colorectal cancer screening with colonoscopy at age 45 years or with fecal immunochemical testing at age 40 years was cost-effective, according to new research.