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Cognitive Impairment

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March 08, 2023
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Investigational drug for Parkinson’s, Lewy body dementia not successful in phase 2 trial

Investigational drug for Parkinson’s, Lewy body dementia not successful in phase 2 trial

Biopharmaceutical company Aptinyx reported its drug for cognitive impairment was not efficacious in a phase 2 clinical trial investigating its use in patients with Parkinson’s disease and Lewy body dementia, according to a press release.

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March 07, 2023
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Perceived stress linked to increased cognitive impairment among Black, white older adults

Perceived stress linked to increased cognitive impairment among Black, white older adults

Perceived stress was associated with both prevalent and incident cognitive function impairment in Black and white older adults, underlining the need for stress assessments among high-risk adults in primary care, according to researchers.

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March 01, 2023
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Cognitive impairment associated with poor asthma control among older adults

Cognitive impairment associated with poor asthma control among older adults

SAN ANTONIO — Elevated cognitive impairment appeared linked to weak asthma control among older adults, according to an abstract presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting.

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February 20, 2023
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Early mobilization during mechanical ventilation reduces risk for cognitive impairment

Early mobilization during mechanical ventilation reduces risk for cognitive impairment

Early mobilization of mechanically ventilated adults lowered the risk for cognitive impairment 1 year following hospital discharge by 19%, according to a study published in The Lancet Respiratory Medicine.

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December 20, 2022
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Vaping-associated lung injury tied to long-term respiratory disability, mood disorders

Vaping-associated lung injury tied to long-term respiratory disability, mood disorders

Patients with e-cigarette- or vaping-associated lung injury, or EVALI, frequently showed long-term cognitive impairment, respiratory limitations and mood disorders, according to a study published in Annals of the American Thoracic Society.

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September 30, 2022
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Chronic inflammation linked to cognitive difficulties among older breast cancer survivors

Chronic inflammation linked to cognitive difficulties among older breast cancer survivors

Higher levels of the inflammatory marker C-reactive protein predicted lower reported cognitive function among older breast cancer survivors, according to study results published in Journal of Clinical Oncology.

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September 04, 2022
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Odds of cognitive impairment increase after stroke in certain populations

Odds of cognitive impairment increase after stroke in certain populations

History of stroke was associated with increased odds of cognitive impairment in both non-Hispanic white and Mexican American individuals, researchers reported.

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August 29, 2022
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Aptinyx completes enrollment of phase 2 trial for oral cognitive impairment treatment

Aptinyx completes enrollment of phase 2 trial for oral cognitive impairment treatment

Aptinyx Inc. announced it has completed enrollment in the company’s ongoing phase 2 study of NYX-458, an oral treatment for cognitive impairment associated with Parkinson’s disease and dementia with Lewy bodies.

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August 17, 2022
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Sleep apnea changes associated with cognitive impairment, brain structure alterations

Sleep apnea changes associated with cognitive impairment, brain structure alterations

Changes in obstructive sleep apnea status were linked with white matter integrity and cognitive performance, suggesting that timely intervention of OSA could help preserve brain health, researchers reported in JAMA Network Open.

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August 08, 2022
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No dementia, cognitive risk with PCSK9 inhibition; statin findings mixed

No dementia, cognitive risk with PCSK9 inhibition; statin findings mixed

Data from a genetics-based study show PCSK9 inhibition does not affect cognition function or dementia risk; however, statin use may be associated with some impaired cognitive performance that is outweighed by any CV benefits.

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