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Cognitive Impairment

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July 13, 2021
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Coya Therapeutics receives orphan drug designation for ALS001

The FDA granted orphan drug designation to ALS001, an autologous, expanded T-cell therapy under development by Coya Therapeutics for treating ALS, according to a press release.

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June 21, 2021
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Statin therapy not associated with dementia, cognitive impairment in older patients

Statin therapy not associated with dementia, cognitive impairment in older patients

Statin therapy was not associated with dementia, mild cognitive impairment and/or any of its subclassifications, according to a secondary analysis of the ASPREE trial of aspirin therapy among older adults.

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June 21, 2021
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One-fifth of patients with MS convert to a worse cognitive phenotype within 5 years

Approximately one-fifth of patients with MS exhibited a deterioration in cognitive status over 5 years, according to results of a cohort study conducted in the Netherlands and published in Neurology.

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June 15, 2021
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Normal-tension glaucoma linked to cognitive impairment

Study results showed an association between normal-tension glaucoma and dementia-related cognitive impairment.

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June 08, 2021
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Belatacept may reverse cognitive impairment in transplant recipients

Belatacept may reverse cognitive impairment in transplant recipients

Transplant recipients who were converted from tacrolimus to belatacept showed improvements in various domains of cognition, suggesting this treatment change may help reverse cognitive impairment.

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April 14, 2021
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Living in highly disadvantaged areas increases brain degeneration, cognitive decline

Living in highly disadvantaged areas increases brain degeneration, cognitive decline

Living in the most disadvantaged neighborhoodss correlated with increased degeneration in Alzheimer’s disease “signature” regions of the brain and cognitive decline, according to the results of a longitudinal study in cognitively healthy adults.

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April 13, 2021
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Physical activity slows cognitive decline in APOE e4 carriers with Parkinson’s disease

Patients with Parkinson’s disease who increased their physical activity saw positive modification of the APOE e4 allele’s impact on early cognitive decline, according to findings from a multicenter cohort study published in Neurology.

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April 08, 2021
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Dual sensory impairment increases risk for dementia, cognitive decline in elderly patients

Dual sensory impairment in vision and hearing increased the rate of dementia and cognitive decline over the course of a 6-year follow-up period, according to findings from a community-based elderly cohort study published in Neurology.

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March 29, 2021
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Obstructive sleep apnea common among patients with cognitive impairment

Obstructive sleep apnea common among patients with cognitive impairment

Obstructive sleep apnea, or OSA, is common among older adults with cognitive impairment, and it was associated lower scores on cognition tests and poorer sleep quality, researchers reported.

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March 08, 2021
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Novel glycine transporter inhibitor effective for improving cognition in schizophrenia

A novel glycine transporter inhibitor improved cognition after 12 weeks among individuals with schizophrenia, according to results of a double-blind, randomized, placebo-controlled phase 2 study published in The Lancet Psychiatry.

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