Cognition
FDA accepts IND with partial clinical hold for oral small molecule Alzheimer’s treatment
The FDA has accepted an investigational new drug application for VG-3927, an oral small molecule TREM2 agonist for the potential treatment of Alzheimer’s disease, according to the manufacturer.
Is menopausal hormone therapy linked with dementia risk? Studies offer conflicting views
PHILADELPHIA — The short-term effects of postmenopausal hormone therapies on the vascular system and the brain may differ from long-term effects and could be influenced by HT formulation and administration route, according to a speaker.
Prior head injury linked to higher risk for cognitive change over 30 years
PHILADELPHIA — Individuals who sustained at least one head injury saw an increased risk for developing cognitive issues over a 30-year period compared to those who did not, according to a poster presentation.
Sleep habits likely play role in cognitive, neurological conditions
PHILADELPHIA — Better sleep boosts quality of life and may have positive long-reaching benefits including reduction of risk for neurological disorders, according to research presented at the American Neurological Association annual meeting.
Sleep 'may be particularly important' for cognition
Better sleep was linked to improved global cognition, highlighting its potential role in maintaining cognitive function for aging adults, according to researchers.
NIH launches clinical trials testing treatments for long COVID symptoms
The NIH announced that it has launched phase 2 clinical trials that will evaluate potential treatments for long COVID conditions as part of its Researching COVID to Enhance Recovery, or RECOVER, initiative.
Exercise combined with cognitive training improves brain health in older adults
Aerobic-resistance exercises combined with cognitive training improved cognition compared with exercise alone in older adults with mild cognitive impairment, a recent study found.
Q&A: Higher dietary nitrate intake linked to reduced risk for dementia
Higher dietary nitrate intake from vegetables was associated with a reduced risk for dementia, according to research published in the American Journal of Clinical Nutrition.
Finger prick test detects blood-based biomarkers of Alzheimer’s disease
A finger prick test measured blood-based biomarkers of Alzheimer’s disease and has potential to increase accessibility of testing, according to research at the Alzheimer’s Association International Conference.
Poor sleep reduces cognitive benefits of exercise
Regular physical activity may protect against cognitive decline, but the benefits may be reduced for those who do not get enough sleep, according to the results of research published in The Lancet Healthy Longevity.