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Clinical Trials

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June 03, 2024
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Advocate discusses how physicians can ‘extend our impact beyond the exam room’

Advocate discusses how physicians can ‘extend our impact beyond the exam room’

According to Ashley L. Sumrall, MD, there’s not a great deal of difference between a practicing oncologist and a physician advocate.

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June 03, 2024
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Opthea completes enrollment in two phase 3 trials of sozinibercept in wet AMD

Opthea completes enrollment in two phase 3 trials of sozinibercept in wet AMD

Opthea has completed enrollment of its phase 3 COAST and ShORe trials, which will investigate the safety and efficacy of sozinibercept in combination with anti-VEGF-A therapy for wet age-related macular degeneration.

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May 30, 2024
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Patient-reported outcomes leveraged to overcome barriers to clinical trial enrollment

Patient-reported outcomes leveraged to overcome barriers to clinical trial enrollment

Participation in cancer-related clinical trials could increase dramatically if researchers screened and recruited individuals using routine care patient-reported outcomes, according to results published in JAMA Oncology.

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May 28, 2024
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VIDEO: Ofatumumab offers sustained efficacy in relapsing MS up to 6 years

VIDEO: Ofatumumab offers sustained efficacy in relapsing MS up to 6 years

DENVER — Early initiation of treatment with ofatumumab showed sustained benefit to those with treatment-naïve relapsing multiple sclerosis, Gabriel Pardo, MD, said in this Healio video from the American Academy of Neurology annual meeting.

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May 22, 2024
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Long-term extension studies seek to further evaluate ALZ-801 for Alzheimer’s disease

Long-term extension studies seek to further evaluate ALZ-801 for Alzheimer’s disease

Alzheon Inc. has enrolled patients who completed either phase 2 or phase 3 trials to evaluate ALZ-801 as a treatment for early Alzheimer’s disease in long-term study extensions, according to a company-issued press release.

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May 22, 2024
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VIDEO: Patients who manage GI disease with special diets ‘need closer follow-up’

VIDEO: Patients who manage GI disease with special diets ‘need closer follow-up’

WASHINGTON — In a Healio video exclusive, Shirley Paski, MD, discusses highlights from her presentation at Digestive Disease Week, which focused on the importance of screening patients on special diets for nutritional risks and malnutrition.

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May 21, 2024
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MiDROPS demonstrates safety, efficacy in phase 2 clinical trial

MiDROPS demonstrates safety, efficacy in phase 2 clinical trial

EyeCRO announced that its Microemulsion Drug Ocular Penetration System, or MiDROPS, demonstrated safety and efficacy in its first clinical application as a topical eye drop vehicle for dry eye disease.

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May 20, 2024
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VIDEO: ‘Clinically significant’ cognitive improvement found with Angelman syndrome drug

VIDEO: ‘Clinically significant’ cognitive improvement found with Angelman syndrome drug

DENVER — Treatment with a novel therapeutic led to clinically significant improvement in cognition for young persons with Angelman syndrome, Kemi Olugemo, MD, FAAN, said in this Healio video at the American Academy of Neurology annual meeting.

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May 19, 2024
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VIDEO: Women, Black patients underrepresented in US-based clinical trials for LT

VIDEO: Women, Black patients underrepresented in US-based clinical trials for LT

WASHINGTON — In a Healio video exclusive, Saqr Alsakarneh, MD, MSc, describes “significant disparities” in race, ethnicity and sex among participants enrolled clinical trials for liver transplantation in the U.S.

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May 14, 2024
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VIDEO: Combination therapy showed favorable safety profile in ALS

VIDEO: Combination therapy showed favorable safety profile in ALS

DENVER — A combination therapy of ciprofloxacin and celecoxib demonstrated a favorable safety profile for those with amyotrophic lateral sclerosis, Merit Cudkowicz, MD, MSc, said in this Healio video.

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