Clinical Trials
FDA clears investigational new drug application for clinical trial of ALS pill
The FDA has cleared an investigational new drug application for a phase 1/2 clinical trial to examine a novel, once-daily pill for the treatment of individuals with amyotrophic lateral sclerosis, according to the manufacturer.
ASCO honoree uses unique vision to improve health equity, train emerging leaders
When Robert A. Winn, MD, learned he’d receive the Allen Lichter Visionary Leader Award at this year’s ASCO Annual Meeting, he reacted in the form of a question: “What just happened?”
VIDEO: Primary generalized tonic-clonic seizures pressing health issue for adolescents
DENVER — Primary generalized tonic-clonic seizures present unique challenges to adolescents diagnosed with the condition, Sunita Misra, MD, PhD, said in this Healio video at the American Academy of Neurology annual meeting.
Advocate discusses how physicians can ‘extend our impact beyond the exam room’
According to Ashley L. Sumrall, MD, there’s not a great deal of difference between a practicing oncologist and a physician advocate.
Opthea completes enrollment in two phase 3 trials of sozinibercept in wet AMD
Opthea has completed enrollment of its phase 3 COAST and ShORe trials, which will investigate the safety and efficacy of sozinibercept in combination with anti-VEGF-A therapy for wet age-related macular degeneration.
Patient-reported outcomes leveraged to overcome barriers to clinical trial enrollment
Participation in cancer-related clinical trials could increase dramatically if researchers screened and recruited individuals using routine care patient-reported outcomes, according to results published in JAMA Oncology.
VIDEO: Ofatumumab offers sustained efficacy in relapsing MS up to 6 years
DENVER — Early initiation of treatment with ofatumumab showed sustained benefit to those with treatment-naïve relapsing multiple sclerosis, Gabriel Pardo, MD, said in this Healio video from the American Academy of Neurology annual meeting.
Long-term extension studies seek to further evaluate ALZ-801 for Alzheimer’s disease
Alzheon Inc. has enrolled patients who completed either phase 2 or phase 3 trials to evaluate ALZ-801 as a treatment for early Alzheimer’s disease in long-term study extensions, according to a company-issued press release.
VIDEO: Patients who manage GI disease with special diets ‘need closer follow-up’
WASHINGTON — In a Healio video exclusive, Shirley Paski, MD, discusses highlights from her presentation at Digestive Disease Week, which focused on the importance of screening patients on special diets for nutritional risks and malnutrition.
MiDROPS demonstrates safety, efficacy in phase 2 clinical trial
EyeCRO announced that its Microemulsion Drug Ocular Penetration System, or MiDROPS, demonstrated safety and efficacy in its first clinical application as a topical eye drop vehicle for dry eye disease.