Clinical Trials

COVID-19 affects men and women differently, yet most current clinical studies of SARS-CoV-2 and the disease do not mention sex or gender, according to an international team of researchers.

The FDA placed a clinical hold on a phase 3 study designed to evaluate elivaldogene autotemcel, an investigational gene therapy, for the treatment of younger patients with cerebral adrenoleukodystrophy.

Pacific Shores Medical Group, one of the nation’s largest hematology/oncology medical groups and infusion programs, has joined City of Hope.

The online tool Outreach Pro was launched at the Alzheimer’s Association International Conference to raise awareness of clinical trials for Alzheimer’s disease and other dementias, specifically in “traditionally underrepresented communities.”

Some changes to cancer clinical trials instituted during the COVID-19 pandemic should have a permanent place in oncology research, according to an article published in Cancer Discovery.

The ADAPTABLE trial, presented and published in May, was notable in two ways: It provided answers on aspirin dosage for patients needing secondary CVD prevention and it showed a large-scale pragmatic trial could work.

In a video exclusive, Remo Panaccione, MD, University of Calgary, outlined new therapeutic data for the treatment of patients with inflammatory bowel diseases at the 16th Congress of European Crohn’s and Colitis Organisation.

The FDA approved an updated label for Aduhelm that emphasizes the disease stages examined in the clinical trials, specifically stating that the agent should be initiated in patients with mild cognitive impairment or dementia.

As part of a partnership to increase clinical trial participation among underserved racial and ethnic groups, ASCO and Association of Community Cancer Centers plan to test a research site-evaluation tool and implicit bias training program.

The multifaceted challenge of increasing diversity in clinical trial enrollment has become a major priority in oncology and is currently being approached from several angles by many institutions, advocacy groups and medical organizations.