Clinical Trials
Longer studies, funding needed to address ‘substantial knowledge gaps’ on PCOS-related CVD
Polycystic ovary syndrome, a common endocrine disorder affecting reproductive-age women, is linked to cardiometabolic disorders that are risk factors for CVD. But the degree of CVD risk in women with polycystic ovary syndrome is still underdetermined.
VIDEO: Several factors apply when selecting patients for clinical trials, expert says
DENVER — In this Healio video, Jessica Ailani, MD, explains that patient selection for clinical trials is not a one-size-fits-all process.
Medicaid expansion under ACA appears to improve cancer clinical trial access
CHICAGO — The Affordable Care Act’s expansion of Medicaid resulted in a nearly threefold increase in the percentage of patients using Medicaid in cancer trials by early 2020, according to study results presented during ASCO Annual Meeting.
Black patients with metastatic breast cancer often not informed of clinical trials
Most Black patients with cancer reported a somewhat or very high likelihood of considering clinical trial participation, yet many had not been informed of the opportunity to enroll onto a clinical trial, study results showed.
NIH awards $12 million to fund clinical trials for AD vaccine
Biotech company PharmaJet announced that its partner, the Institute for Molecular Medicine, was awarded a $12 million grant from the NIH National Institute on Aging for a vaccine to prevent Alzheimer’s disease.
Cancer organizations issue recommendations to increase clinical trial diversity
ASCO and the Association of Community Cancer Centers have jointly developed recommendations for improving equity, diversity and inclusion in cancer clinical trials.
Efficacy vs. effectiveness: Registry data key to which drugs are useful in real world
The key to better understanding the efficacy vs. effectiveness gap in drug therapies could lie in real-world data and patient registries, according to a speaker at the FDA & American College of Rheumatology Virtual Summit.
Tenecteplase inferior to alteplase for moderate, severe acute ischemic stroke
In patients with moderate or severe ischemic stroke, a lower dose of IV tenecteplase yielded less favorable functional outcomes compared to a higher standard dose of alteplase, according to data published in The Lancet Neurology.
VIDEO: Virtual platforms may boost enrollment, encourage diversity in clinical trials
In this video exclusive, Aasma Shaukat, MD, MPH, professor at NYU Grossman School of Medicine, discusses how her group achieved diverse enrollment for PREEMPT CRC, a study designed to validate a blood test for colorectal cancer screening.
FDA releases draft guidance for drugs under development for celiac disease
The FDA has issued a draft guidance for sponsors developing drugs as adjunctive treatment to a gluten-free diet in adults with celiac disease.