Clinical Trials
First patient enrolled in phase 1/2 study of hydroxyl dendrimer imaging agent
Ashvattha Therapeutics announced that the first patient has been enrolled in a phase 1/2 study to evaluate the ability of an imaging agent to cross the blood-brain barrier and target key markers of neuroinflammation.
FDA grants orphan drug designation for facioscapulohumeral muscular dystrophy treatment
The FDA has granted orphan drug designation to Avidity Biosciences Inc. for AOC 1020, its novel RNA therapeutic to treat facioscapulohumeral muscular dystrophy.
Cognivue reports nearly 40% participation rate from marginalized groups in FOCUS study
The national Further the Objective and Clinical Understanding of Cognivue Study drew a 37% research participation rate from individuals in underserved and underrepresented populations, the neuroscience company reported in a press release.
NCI-funded clinical trials add 14.2M life-years for patients with cancer over 4 decades
Clinical trials performed within the NCI’s National Clinical Trials Network during the past 40 years prolonged the lives of patients with cancer by at least 14.2 million life-years, according to a study in Journal of Clinical Oncology.
Athira announces clinical trials for Alzheimer’s, Parkinson’s, ALS treatments in 2023
Athira Pharma Inc. revealed its list of planned clinical trials for 2023, which include development of therapeutics for Alzheimer’s disease, Parkinson’s disease and ALS.
Strategies aim to reduce barriers to care, increase trial diversity
World Cancer Day is observed annually on Feb. 4.
Restoring Trust in the Health Care System with Christopher Heery, MD
In this episode, host Shikha Jain, MD, speaks with Christopher Heery, MD, of Arcellx, Inc. about making the transition from physician to chief medical officer, providing more access and education for clinical trials and more.
Study yields insights into patient perceptions of cancer clinical trial benefits, burdens
Patient withdrawal from cancer clinical trials can result in systematic bias, insufficiently powered studies and a loss of valuable scientific knowledge, according to a study in JAMA Network Open.
Women widely underrepresented in stroke trial leadership
An analysis of hundreds of stroke trials shows significantly more men than women were registered as principal investigators from 2011 to 2020, with the most striking difference observed for acute stroke trials, researchers reported.
First participants dosed in phase 1 study of nasal spray for treatment of MDD
A biopharmaceutical company announced the first participants have been dosed in its phase 1 clinical trial of PH10, an investigational pherine nasal spray to treat major depressive disorder.