Clinical Trials

Horizon Therapeutics recently announced new MRI imaging data from a phase 3 clinical trial, which demonstrated that Uplizna reduced formation of asymptomatic optic nerve lesions in patients with neuromyelitis optica spectrum disorder.

Treatment with zavegepant 10 mg nasal spray was safe, well-tolerated and provided pain and symptom relief for moderate to severe migraine compared with placebo, according to a study published in The Lancet Neurology.

Azstarys had a favorable safety profile, demonstrated efficacy and was well-tolerated compared to other methylphenidate products over 1 year of treatment, according to research presented in the Journal of Child and Adolescent Psychopharmacology.

In older adults with treatment-resistant depression, antidepressant augmentation improved well-being significantly over 10 weeks compared with switching medications and was associated with higher incidence of remission.

A Kansas-based biopharmaceutical company has announced positive top-line results from a study assessing the effect of food on absorption of its investigational extended-release tablet therapeutic CTx-1301 to treat ADHD.

The FDA has approved Skyclarys, Reata Pharmaceuticals’ oral, once-daily medication to treat Friedreich’s ataxia in people aged 16 years and older.

CVD is responsible for approximately one in three deaths among women in the U.S. each year, yet only 38% of participants in clinical CVD trials are women, according to the American Heart Association.

SAN DIEGO — A systematic review of 25 years of MS-related clinical studies revealed a lack of diversity, inclusion and representation, which can affect patient treatment and outcomes, according to a presenter at ACTRIMS 2023.

SAN DIEGO — Evidence over the past 10 years supports the role of Epstein-Barr virus in the development of MS, according to a presenter at ACTRIMS 2023.

Viz.ai announced a collaboration with BIOS Clinical Trials Coordinating Center at Johns Hopkins University to facilitate patient enrollment for the NIH-funded Biomarker and Edema Attenuation in Intracerebral Hemorrhage study.