Clinical Trials

SAN DIEGO — People from underrepresented racial and ethnic groups participate in clinical trials at extremely low rates, and trialists have a duty to ensure participants reflect the larger community, according to a speaker.

The FDA has approved Elevidys, a recombinant gene therapy for pediatric patients with Duchenne muscular dystrophy and confirmed gene mutation who do not have a pre-existing medical reason preventing treatment.

Editor’s note: This is the second in a series of five stories from ASCO Voices, a session during ASCO Annual Meeting focused on the human side of oncology.

Rates of withdrawal of consent from cancer clinical trials remained below 10% between 2013 and 2019, according to data published in JAMA Oncology.

AUSTIN, Texas — Atogepant significantly improved daily functioning and reduced physical impairment in adults with chronic migraine within 1 week of treatment, according to study results presented here by Jessica Ailani, MD.

In this episode, host Shikha Jain, MD, speaks with Medidata’s Alicia Staley about enhancing the patient care experience from a former patient’s perspective, building empathetic technical solutions and more.

Halozyme Therapeutics announced that argenx received FDA approval for Vyvgart Hytrulo with Enhanze for subcutaneous use in adults with generalized myasthenia gravis who are anti-acetylcholine receptor antibody positive.

Women were underrepresented as principal investigators in total hip and total knee arthroplasty clinical trials which may lead to disparities in academic promotion and advancement, according to published results.

A networking group created for cardiology fellows-in-training has successfully engaged trainees with clinical trial programs, serving as a model to help diversify recruitment and representation in trials, researchers reported.

The number of cancer survivors diagnosed with a new malignancy increased by 15% from 2013 to 2019, according to data published in JAMA Oncology.