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March 21, 2024
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Most U.S. cancer trials conducted in more affluent, less diverse areas

Most U.S. cancer trials conducted in more affluent, less diverse areas

Most of the major cancer clinical trial centers in the U.S. are located near more affluent and white populations compared with the national average, according to results published in JAMA Oncology.

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March 19, 2024
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Evobrutinib nonsuperior to teriflunomide for relapsing forms of MS

Evobrutinib nonsuperior to teriflunomide for relapsing forms of MS

WEST PALM BEACH, Fla. — Treatment with evobrutinib was nonsuperior to teriflunomide in confirmed disability progression at 12 and 24 weeks for those with relapsing forms of multiple sclerosis, according to a presenter at ACTRIMS 2024.

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March 17, 2024
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Oncologists discuss ‘magic wand’ solutions to improve clinical trial diversity

Oncologists discuss ‘magic wand’ solutions to improve clinical trial diversity

An FDA Oncology Center of Excellence program titled “Real Talk: Our Stories as Black Oncologists at the FDA” included discussion about how to increase diversity in clinical trials.

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March 12, 2024
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Nusinersen linked to improved motor function in spinal muscular atrophy

Nusinersen linked to improved motor function in spinal muscular atrophy

Treatment with nusinersen was linked to increased motor function and reduction of the neurodegenerative biomarker neurofilament light chain in children with spinal muscular atrophy, according to interim results of a study.

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March 06, 2024
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Viltolarsen linked to increased pulmonary function in Duchenne muscular dystrophy

Viltolarsen linked to increased pulmonary function in Duchenne muscular dystrophy

Treatment with viltolarsen at 48 weeks improved pulmonary function in a cohort of pediatric patients with Duchenne muscular dystrophy amenable to exon 53 skipping compared with those receiving standard care.

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March 04, 2024
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Zolgensma improves motor function at 52 weeks in spinal muscular atrophy

Zolgensma improves motor function at 52 weeks in spinal muscular atrophy

Treatment with Zolgensma improved motor function in a cohort of children with spinal muscular atrophy, according to a poster at the 2024 MDA Clinical & Scientific Conference.

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March 04, 2024
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Pamrevlumab nonsuperior to placebo for boys with Duchenne muscular dystrophy

Pamrevlumab nonsuperior to placebo for boys with Duchenne muscular dystrophy

For young ambulatory boys with Duchenne muscular dystrophy, treatment with pamrevlumab was nonsuperior to placebo after 52 weeks, according to a poster presentation at the 2024 MDA Clinical & Scientific Conference.

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February 27, 2024
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Atogepant well-tolerated, linked to significant migraine reduction

Atogepant well-tolerated, linked to significant migraine reduction

Treatment with atogepant was safe, effective and well-tolerated over 12 weeks in those with episodic migraine who failed multiple conventional therapies, with significant reductions in mean monthly migraine days compared with placebo.

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February 26, 2024
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Quolet completes phase 1 study of oral, lipid-based CBD in healthy volunteers

Quolet completes phase 1 study of oral, lipid-based CBD in healthy volunteers

Quolet Industries has announced the completion of a phase 1 study evaluating a novel, lipid formulation of pure CBD as a potential treatment for various psychiatric and neurologic conditions.

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February 23, 2024
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Biopharma firm to commence phase 2 study of oral small molecule drug for Parkinson’s

Biopharma firm to commence phase 2 study of oral small molecule drug for Parkinson’s

A New York-based biopharmaceutical company has received a grant from Cure Parkinson’s to initiate a phase 2 clinical trial investigating dapansutrile, an oral small molecule, as a disease-modifying therapy for Parkinson’s disease.

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