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November 19, 2024
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Daily dose of oral edaravone for ALS nonsuperior to staggered regimen at 48 weeks

Daily dose of oral edaravone for ALS nonsuperior to staggered regimen at 48 weeks

For individuals with ALS, a daily dosing regimen of oral edaravone was nonsuperior to an FDA-approved staggered regimen of the drug plus placebo, according to a poster presented at AANEM.

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November 14, 2024
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Blarcamesine slows clinical decline in Alzheimer’s disease

Blarcamesine slows clinical decline in Alzheimer’s disease

Treatment with oral blarcamesine for older adults with Alzheimer’s disease led to significant slowing of clinical decline compared with placebo at 48 weeks, according to new research presented at CTAD.

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November 14, 2024
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Q&A: New Pulmonary Fibrosis Foundation chief medical officer to focus on community

Q&A: New Pulmonary Fibrosis Foundation chief medical officer to focus on community

Amy Hajari Case, MD, FCCP, has been named chief medical officer of the Pulmonary Fibrosis Foundation, according to a press release.

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November 13, 2024
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Koselugo significantly reduces neurofibromas in ongoing phase 3 study

Koselugo significantly reduces neurofibromas in ongoing phase 3 study

An oral therapeutic significantly reduced the number of tumors in adults with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas, according to topline results from a phase 3 study.

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November 07, 2024
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Uplizna treatment shows greater improvement in myasthenia gravis compared with placebo

Uplizna treatment shows greater improvement in myasthenia gravis compared with placebo

IV administration of Uplizna was safe and shown to be more efficacious for those with generalized myasthenia gravis compared with placebo at week 26, according to a presentation from AANEM.

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November 06, 2024
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IV administration of fasudil safe, well tolerated in ALS

IV administration of fasudil safe, well tolerated in ALS

IV administration of fasudil at two separate doses was safe and well tolerated in a small cohort of individuals with suspected or confirmed ALS, according to new research published in The Lancet.

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November 01, 2024
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VIDEO: Experts consider endpoints for clinical trials in geographic atrophy

VIDEO: Experts consider endpoints for clinical trials in geographic atrophy

CHICAGO — In this video, Joan W. Miller, MD, chair of ophthalmology at Mass Eye and Ear, discusses highlights from the AAO meeting.

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October 31, 2024
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Personalized TMS leads to 44% slowing of Alzheimer’s progression at 1 year

Personalized TMS leads to 44% slowing of Alzheimer’s progression at 1 year

Treatment with non-invasive, personalized repetitive transcranial magnetic stimulation in those with mild to moderate Alzheimer’s resulted in a 44% slowing of disease progression at 52 weeks, according to the manufacturer.

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October 24, 2024
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Many patients with cancer do not have access to clinical trials based on where they live

Many patients with cancer do not have access to clinical trials based on where they live

Most counties in the United States do not have active cancer clinical trials, according to results of an ASCO analysis.

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October 23, 2024
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EMA grants orphan drug designation to spinal and bulbar muscular atrophy drug

EMA grants orphan drug designation to spinal and bulbar muscular atrophy drug

The European Medicines Agency has granted orphan drug designation to a small molecule intended to treat spinal and bulbar muscular atrophy, according to the manufacturer.

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