Clarithromycin
ACG updates guideline for managing H. pylori in treatment-naive, experienced patients
The ACG has released a new clinical practice guideline that summarizes therapy options and recommendations for both treatment-naive and treatment-experienced patients with active Helicobacter pylori infection, as well as testing concerns.
Vonoprazan-bismuth triple therapy eradicates H. pylori in up to 90.9% vs. standard care
A triple therapy of vonoprazan, amoxicillin and bismuth potassium citrate achieved an eradication rate of just over 90%, similar to that of the standard quadruple therapy, in patients with Helicobacter pylori infection, according to data.
Treatment for H. pylori infection may yield ‘notable’ survival benefits in gastric cancer
Treatment for Helicobacter pylori was associated with improved overall and disease-free survival among patients with confirmed infection and gastric cancer who underwent gastrectomy, according to data published in JAMA Network Open.
H. pylori antibiotic resistance increases in Europe
Top in cardiology: Hemorrhagic risk with clarithromycin use, stroke risk in black smokers
Researchers observed a small but significant increased risk for major hemorrhage in older patients on direct oral anticoagulant therapy who received clarithromycin vs. azithromycin. It was the top story in cardiology last week.
Clarithromycin, direct oral anticoagulant concomitant use may confer hemorrhagic risk
Among older patients on a direct oral anticoagulant, those who took clarithromycin had a small, statistically significant increased risk for major hemorrhage at 30 days vs. those taking azithromycin, researchers found.