Cisplatin

The addition of concurrent cisplatin to adjuvant radiation therapy conferred no benefit to women with intermediate-risk, early-stage cervical cancer who underwent radical hysterectomy, according to randomized phase 3 study results.

Findings presented at ASCO Quality Care Symposium provided new insights into the effects last year’s cisplatin shortage had on patients with head and neck cancer.

Two common platinum-based chemotherapies that had been in short supply for most of the past year are much more widely available this summer, according to results of a new National Comprehensive Cancer Network survey.

To address ongoing chemotherapy drug shortages, ASCO convened a multidisciplinary panel of oncologists, ethicists and patient advocates to expedite clinical guidance for navigating care where rationing or alternative therapies are needed.

The FDA approved pembrolizumab in combination with gemcitabine and cisplatin chemotherapy for adults with locally advanced unresectable or metastatic biliary tract cancer.

Most U.S. cancer centers reported experiencing a shortage of at least one type of oncology drug, according to the results of a National Comprehensive Cancer Network survey on chemotherapy shortages.

Patients with muscle-invasive bladder cancer receiving dose-dense methotrexate, vinblastine, doxorubicin and cisplatinhad improved OS at 5 years compared with gemcitabine and cisplatin, according to a presentation at ASCO Annual Meeting.

Healio spoke with Karen L. Reckamp, MD, professor in medicine and director of the division of medical oncology at Cedars-Sinai Medical Center, about key studies in lung cancer from ASCO Annual Meeting.

A gene signature model appeared to predict response to cisplatin chemotherapy among tumor samples from patients with muscle-invasive bladder cancer, according to early-phase study results.

ASCO Chief Medical Officer Julie R. Gralow, MD, FACP, FASCO, urged members of Congress to take action on cancer drug shortages, which she described as the worst she has witnessed during her 30-year career in oncology.