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Circulating Tumor Dna

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December 13, 2021
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Circulating tumor DNA profiling may allow for surgery-free detection of CNS lymphoma

Circulating tumor DNA profiling may allow for surgery-free detection of CNS lymphoma

Circulating tumor DNA can be readily detected in patients with central nervous system lymphoma and may be a strong clinical biomarker for risk stratification, outcomes prediction and surgery-free lymphoma classification, results showed.

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October 18, 2021
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ctDNA reduction after tebentafusp predicts OS in uveal melanoma

ctDNA reduction after tebentafusp predicts OS in uveal melanoma

Reduction in circulating tumor DNA appeared correlated with longer OS among patients with previously treated metastatic uveal melanoma who received tebentafusp, according to study results presented at the virtual ESMO Congress.

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September 28, 2021
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Blood test may predict response to CAR T-cell therapy

Blood test may predict response to CAR T-cell therapy

Patients with diffuse large B-cell lymphoma who achieved a durable response to axicabtagene ciloleucel showed evidence of lower circulating tumor DNA levels before and after treatment, according to results of a prospective study.

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September 24, 2021
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Whole-genome methylation shows promise as multicancer early-detection test

Whole-genome methylation shows promise as multicancer early-detection test

Evaluation of multiple classifiers, both alone and in combination, supports the decision to focus on cell-free DNA methylation patterns to detect cancer and predict the cancer signal origin, according to a presentation at ESMO Congress 2021.

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September 03, 2021
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Multicancer screening tests: Not ready for prime time

Multicancer screening tests: Not ready for prime time

Scientists have made amazing advances in recent years in understanding the molecular biology of cancer.

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August 11, 2021
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CtDNA possible biomarker to predict relapse in multiple myeloma

Using circulating tumor DNA to predict relapse after autologous stem cell transplantation in patients with multiple myeloma showed feasibility in a study presented at the virtual ASCO Annual Meeting.

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April 08, 2021
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VIDEO: Important developments underway in breast cancer

VIDEO: Important developments underway in breast cancer

Healio spoke with Debu Tripathy, MD, about treatments being developed for breast cancer.

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February 15, 2021
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Circulating tumor DNA could help guide treatment of BRAF V600-mutant metastatic melanoma

Circulating tumor DNA could help guide treatment of <i>BRAF</i> V600-mutant metastatic melanoma

Circulating tumor DNA measurements before and during treatment could help guide selection of therapy for patients with BRAF V600-mutant unresectable or metastatic melanoma, according to study results published in The Lancet Oncology.

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January 22, 2021
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Circulating tumor DNA predicts relapse risk among patients with colorectal cancer

Circulating tumor DNA predicts relapse risk among patients with colorectal cancer

Circulating tumor DNA analysis outperformed an established biomarker in predicting risk for colorectal cancer recurrence after surgery, according to study results presented at Gastrointestinal Cancers Symposium.

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December 17, 2020
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VIDEO: Circulating tumor DNA possible biomarker for relapse in DLBCL

VIDEO: Circulating tumor DNA possible biomarker for relapse in DLBCL

Detection of circulating tumor DNA using immunoglobulin-based next generation sequencing within an apheresis stem cell sample predicted relapse after autologous stem cell transplantation among patients with diffuse large B-cell lymphoma.

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