Chronic Kidney Disease

At 2 years following transcatheter aortic valve replacement, nonagenarians experienced no greater risk for mortality or stroke than younger patients, despite being at greater surgical risk, researchers reported.

Group-based care for the management of chronic kidney disease may be a promising alternative to usual nephrology care alone in adult patients, according to findings in a recently published study.

Heart failure hospitalizations and eGFR decline are associated with anemic patients with chronic kidney disease, according to an abstract from the virtual National Kidney Foundation Spring Clinical Meetings.

No clinically relevant changes were found with vadadustat pharmacokinetic exposure following co-administration of rabeprazole and vadadustat, according to a speaker at the virtual National Kidney Foundation Spring Clinical Meetings.

The prevalence of obesity is growing worldwide among children, adolescents and adults.1-6 People with obesity in the general population are at an increased risk of various adverse health concerns, including diabetes mellitus, hypertension, cardiovascular disease, depression and kidney disease.7-13 Kovesdy, Furth and Zoccali published a review in 2017 of numerous studies that demonstrated the association between measures of obesity and the development and progression of chronic kidney disease. They indicated recommendations appear to be justified for lifestyle modifications to reduce body weight in obese people at risk of CKD and those with early stages of CKD (particularly for the control of diabetes and hypertension).13

Through a partnership with the Pathways Project, in collaboration with the Coalition for Supportive Care of Kidney Patients, a Dallas-based nephrology practice has identified ways to tailor advance care planning to the individual patient. The methods, which assessed using “small tests of change,” were presented at the virtual National Kidney Foundation Spring Clinical Meetings.

For patients with diabetic kidney disease, using an artificial intelligence-enabled diagnostic test to predict rapid kidney function decline and kidney failure could result in substantial savings to the U.S. health care system, a speaker told the audience at the virtual National Kidney Foundation Spring Clinical Meetings.

For patients with chronic kidney disease and diabetes, veverimer appeared to be an effective treatment for metabolic acidosis, as it improved both quality of life and physical function, according to phase 3 trial results. The results were presented virtually at the National Kidney Foundation Spring Clinical Meetings.

Use of the oral hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat helped reduce the need for red blood cell transfusions compared to placebo in patients with chronic kidney disease not on dialysis, studies show.

According to a national survey commissioned by Fresenius Medical Care North America, there is a significant gap between the desire and the ability of Americans with chronic kidney disease to age “in place,” which the survey considered to be the ability of adults to live in their existing homes or communities despite patient age, income or physical mobility.