Chronic Kidney Disease
Machine learning identifies three CKD subgroups for more precise risk stratification
A machine learning algorithm grouped patients with chronic kidney disease into three distinct subgroups. Each subgroup was associated with different risks for disease progression, cardiovascular events and mortality.
CKD progression risk ‘modest’ with bisphosphonate use
Adults with chronic kidney disease stage 3b were more likely to experience a worsening of renal function when prescribed bisphosphonate therapy, according to a database analysis published in the Journal of Bone and Mineral Research.
Monitoring approach for 2 weeks improves understanding of CKD-related arrythmias
For patients with chronic kidney disease, the use of a 2-week continuous electrocardiogram monitoring device led to the identification of a “broader range” of arrhythmias than had been previously reported.
Excluding race in GFR equations leads to ‘substantial’ rise in estimated CKD prevalence
After assessing kidney function in a sample of self-identified Black adults, researchers found excluding race from the calculations led to a “substantial increase” in estimated prevalence of chronic kidney disease.
Excluding race in GFR equations leads to ‘substantial’ rise in estimated CKD prevalence
After assessing kidney function in a sample of self-identified Black adults, researchers found excluding race from the calculations led to a “substantial increase” in estimated prevalence of chronic kidney disease.
Phosphate-lowering drug may increase blood pressure in patients with CKD
Phosphate binder lanthanum carbonate increased systolic blood pressure in patients with chronic kidney disease, leading researchers to suggest the drug “may reduce gastrointestinal absorption of antihypertensive medications.”
Diabetes complications differ according to ethnicity, disease-related subgroups
Risks for diabetes complications vary according to subgroups related to age of onset, HbA1c, obesity and insulin use, and there are racial and ethnic disparities in the composition of each subgroup, according to study data.
Serum magnesium levels linked to mortality risk in patients with CKD
Men are at greater risk for CKD progression, mortality vs women
Men with chronic kidney disease were more likely to experience disease progression and mortality compared with women, according to results of a 10-year observational study conducted in Sweden.
eGFR variability linked to greater mortality risk but not cardiovascular events
For patients with hypertension, variation in eGFR measurements over time appeared to increase risk for all-cause mortality but did not demonstrate an association with cardiovascular events.