Chronic Egfr Decline

Donor-derived cell-free DNA was determined to be a leading indicator of allograft injury, eGFR decline, formation of de novo donor-specific antibodies and subclinical rejection, according to published data.

The incidence of asymptomatic pyuria is correlated with rapid decline in kidney function irrespective of the autosomal dominant polycystic kidney disease genotype and cystic growth.

The investigational drug, bardoxolone methyl preserved kidney function in patients and provided eGFR benefits for those with chronic kidney disease, according to an oral abstract presentation given as part of ASN Kidney Week.

Defining hypothyroidism by thyroid-stimulating hormone level, researchers found the condition was more common in patients with worsening levels of kidney function (as determined by eGFR slope), as well as in those who had proteinuria.

Following hospitalization with COVID-19, remdesivir improved kidney function in most patients with eGFRs of less than 30 mL/min/1.73 m2 and was generally well-tolerated, according to study findings.

Study findings suggest Black and Hispanic patients are at greater risk for developing kidney failure due to faster decline in kidney function following chronic kidney disease onset vs. white patients.

WASHINGTON — Research presented at ASN Kidney Week suggested a machine learning model that combines blood biomarkers and electronic health record data performed better in predicting rapid kidney function decline in patients with type 2 diabetes than other commonly used models.