Cholesterol

Older adults had a 16% lower risk for developing parkinsonism after taking statins for 6 years compared with those not on statins, a report published in Neurology showed.

In patients with heterozygous familial hypercholesterolemia already taking maximally tolerated lipid-lowering medication, resmetirom lowered LDL, triglycerides, apolipoprotein B and lipoprotein(a) levels vs. placebo, researchers reported.

More intensive LDL cholesterol–lowering statin-based therapies may benefit patients with ischemic stroke with evidence of atherosclerosis, according to a meta-analysis published in JAMA Neurology.

Substituting a small portion of food with nutrient-dense foods may effectively lower cholesterol among patients with hyperlipidemia without the use of drugs, according to findings published in the Journal of Nutrition.

Among patients with predisposing factors for HF, aspirin use was associated with a 26% increased risk for HF development, researchers reported in ESC Heart Failure.

In two early clinical studies, the first version of an oral PCSK9 inhibitor was well tolerated and effective for reducing LDL, according to phase 1 data reported at the American Heart Association Scientific Sessions.

Maternal cholesterol during pregnancy was an independent risk factor for acute MI severity in young adult offspring, according to study results published in the European Journal of Preventive Cardiology.

Walnut consumption and lipid levels in older individuals.

In an update on FDA approvals and late-breaking trials in lipid therapies, a speaker reviewed the current and future landscapes of LDL- and triglyceride-lowering therapies.

Over 20 years, CVD risk and CV risk factor prevalence was greater in Black Americans compared with white Americans, though the difference may have been mediated by social determinants of health, researchers reported.