Childrens Hospital Of Philadelphia

Constipation is a relatively common problem in pediatric practice, with reported prevalence rates between 1% and 30%, as well as the chief complaint in 3% to 5% of visits to pediatric outpatient clinics. Because most constipation cases can be remedied through recommended over-the-counter laxatives, constipation is rarely a cause for severe worry among parents.

There is no gold standard outcome to guide care for unrecognized clinical deterioration outside the ICU among hospitalized children despite the high risk for morbidity and mortality these patients face, experts noted recently in Pediatrics.

Researchers at Children’s Hospital of Philadelphia and Perelman School of Medicine at University of Pennsylvania developed an in vivo proof-of-concept model for the delivery of gene editing tools to treat blood disorders.

Following SARS-CoV-2 infection, mitochondrial function remained impaired in the heart, liver and kidneys, despite observed recovery in the lungs, according to a human autopsy and animal tissue study.

Electronic health record-based nudges aimed at clinicians appeared to increase tobacco use treatment penetration among patients with cancer during oncology encounters, according to data published in Journal of Clinical Oncology.

Children’s Hospital of Philadelphia was named the top hospital for pediatric orthopedics in the 2023 to 2024 rankings by U.S. News & World Report.

Cincinnati Children’s Hospital Medical Center has been ranked the No. 1 children’s hospital for cancer in the country.

Lorlatinib appeared safe and showed potential efficacy among a cohort of patients with relapsed or refractory, ALK-driven, high-risk neuroblastoma, results of a phase 1 trial showed.

Advances in pediatric cancer research and treatment over the past 50 years have led to dramatic improvements in survival outcomes for this vulnerable population.

Children who underwent implantation of a transcatheter leadless pacemaker experienced implant success, good electrical performance and a low level of major complications during short-term follow-up, real-world data show.