Chemotherapy
MRI has ‘big upside’ predicting which patients with rectal cancer could avoid surgery
MRI can help identify which patients with rectal cancer could avoid surgery based on response to neoadjuvant therapy, according to study results.
Blood test may improve detection of early pancreatic cancer
A novel evaluation of biomarkers known to be associated with pancreatic cancer significantly improved detection of early-stage disease compared with previous tests, according to results of a double-blind phase 2 trial.
CAR T-cell therapy produces ‘jaw dropping’ results for deadly pediatric brain tumors
Chimeric antigen receptor T-cell therapy can reduce tumor burden and improve neurologic function for patients with certain brain and spinal cord cancers, a first-in-human clinical trial showed.
Cadonilimab regimen extends survival in advanced cervical cancer
The addition of cadonilimab to first-line chemotherapy improved outcomes among certain women with cervical cancer.
FDA approves obecabtagene autoleucel for adult leukemia treatment
The FDA has approved obecabtagene autoleucel for the treatment of adults with relapsed refractory B-cell precursor acute lymphoblastic leukemia.
De-escalated adjuvant chemotherapy effective for high-risk retinoblastoma
A shortened adjuvant chemotherapy regimen improved outcomes for infants with unilateral pathologic high-risk retinoblastoma, according to study results.
Community medical centers can safely administer CAR-T, but extensive preparation required
Chimeric antigen receptor T-cell therapy can be administered at community centers and on an outpatient basis with proper preparation, education and resources, according to prospective study results.
Serious adverse event risk after egg freezing similar for women with vs. without cancer
DENVER — Women with cancer had similar serious adverse event risk as women without cancer after undergoing fertility preservation procedures, according to study results presented at the ASRM Scientific Congress & Expo.
Aerobic exercise may improve cognitive function for women who undergo chemotherapy
Women with breast cancer who began an aerobic exercise program at the start of chemotherapy self-reported improved cognitive function and quality of life, according to results of a randomized trial.
Neoadjuvant immune checkpoint inhibitor therapy improves outcomes in early breast cancer
The addition of immune checkpoint inhibitor therapy to neoadjuvant chemotherapy improved pathologic complete response and EFS for certain patients with early-stage breast cancer, according to a systematic review and meta-analysis.