Chemotherapy

Healio spoke with Joshua Brody, MD, about unmet needs and distinct challenges, as well as the treatment landscape in diffuse large B-cell lymphoma.

Healio spoke with Joshua Brody, MD, about unmet needs and distinct challenges, as well as the treatment landscape in diffuse large B-cell lymphoma.

NEW ORLEANS — Consolidation therapy with high-dose chemotherapy followed by hematopoietic stem cell transplant significantly prolonged PFS among adults with primary central nervous system lymphoma, according to study results.

Infants with Artemis-deficient severe combined immunodeficiency improved after corrected genes in their stem cells enabled them to grow their own T cells and B cells, according to a study published in The New England Journal of Medicine.

Trifluridine-tipiracil plus bevacizumab was not superior to capecitabine plus bevacizumab but presented no new safety concerns in patients with unresectable metastatic colorectal cancer who are ineligible for intensive treatment.

In this edition, fludarabine has been placed on the FDA’s drug shortage list; epcoritamab is approved for advanced lymphoma; pembrolizumab with chemotherapy improves OS in gastric cancer, and more.

During their lifetime, one in 70 women will receive a diagnosis of ovarian cancer, which is the second most common gynecologic cancer in the United States, according to Memorial Sloan Kettering Cancer Center.

A physical exercise intervention delivered during chemotherapy was associated with a return to similar levels of baseline cardiorespiratory fitness at 1 year compared with exercise after chemotherapy, researchers reported.

Women who use taxane chemotherapy agents may be at a higher risk to develop epiphora, optic neuropathy and cystoid macular edema, according to a study.

More than half of adults who underwent chemotherapy for breast, gastrointestinal, gynecologic or lung cancer had confirmed hearing loss, and more than 35% had tinnitus, according to data published in BMJ Supportive & Palliative Care.