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Chemotherapy

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April 21, 2023
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Perioperative toripalimab regimen extends EFS in resectable stage III NSCLC

Perioperative toripalimab regimen extends EFS in resectable stage III NSCLC

A combination of toripalimab and perioperative chemotherapy significantly extended EFS compared with chemotherapy alone among patients with resectable stage III non-small cell lung cancer, according to results of a randomized phase 3 study.

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April 20, 2023
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VIDEO: Exploring treatment options in metastatic triple-negative breast cancer

VIDEO: Exploring treatment options in metastatic triple-negative breast cancer

Healio spoke with Ahmed Elkhanany, MD, about treatment options available in metastatic triple-negative breast cancer.

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April 20, 2023
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VIDEO: Treatment of metastatic triple-negative breast cancer has 'changed drastically'

VIDEO: Treatment of metastatic triple-negative breast cancer has 'changed drastically'

Healio spoke with Ahmed Elkhanany, MD, about recent advancements in metastatic triple-negative breast cancer.

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April 18, 2023
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Adding panitumumab vs. bevacizumab to chemotherapy extends OS in colorectal cancer subset

Adding panitumumab vs. bevacizumab to chemotherapy extends OS in colorectal cancer subset

The addition of panitumumab vs. bevacizumab to standard first-line chemotherapy significantly extended OS for certain patients with RAS wild-type metastatic colorectal cancer, according to data published in JAMA.

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April 14, 2023
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Black patients may be at elevated cardiotoxicity, HF risk after chemotherapy

Black patients may be at elevated cardiotoxicity, HF risk after chemotherapy

Results of a large meta-analysis indicated that Black race was associated with greater odds of cardiotoxicity and HF diagnosis after chemotherapy compared with white and non-Black race, a speaker reported.

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April 11, 2023
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Amid drug shortage, chemotherapy regimen a viable alternative for high-risk bladder cancer

Amid drug shortage, chemotherapy regimen a viable alternative for high-risk bladder cancer

The combination of gemcitabine and docetaxel conferred superior high-grade recurrence-free survival compared with standard therapy among adults with high-risk nonmuscle-invasive bladder cancer, results of a retrospective study showed.

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April 10, 2023
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Perichemotherapy antibiotics improve PDAC survival in patients treated with gemcitabine

Perichemotherapy antibiotics improve PDAC survival in patients treated with gemcitabine

Receipt of perichemotherapy antibiotics correlated with improved survival in patients with metastatic pancreatic ductal adenocarcinoma treated with gemcitabine, but not fluorouracil, according to results in JAMA Network Open.

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April 06, 2023
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AI-identified histologic feature may offer ‘prognostic value,’ inform care in colon cancer

AI-identified histologic feature may offer ‘prognostic value,’ inform care in colon cancer

A prognostic study validated the use of an artificial intelligence-derived tumor adipose feature, which may aid risk stratification of colon cancer and provide prognostic value when integrated into practice, according to study results.

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March 30, 2023
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Nivolumab plus chemotherapy confers sustained benefit for patients with NSCLC

Nivolumab plus chemotherapy confers sustained benefit for patients with NSCLC

Neoadjuvant nivolumab plus platinum-based chemotherapy conferred sustained clinical benefit for patients with resectable non-small cell lung cancer, 3-year follow-up results of the phase 3 CheckMate -816 trial showed.

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March 30, 2023
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Response to neoadjuvant chemotherapy worse for Black women with certain breast cancers

Response to neoadjuvant chemotherapy worse for Black women with certain breast cancers

Racial and ethnic subtype-specific differences in pathologic complete response rates after neoadjuvant chemotherapy for breast cancer may partially account for worse survival rates for Black women, according to study data.

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