Chemotherapy
Efforts to improve oral chemotherapy adherence target multilevel barriers
Development and use of oral chemotherapy medications has increased substantially over the past decade, offering many patients with cancer a more convenient and less stressful treatment option.
Severe myelosuppression common after chemotherapy for small cell lung cancer
Nearly all individuals who received chemotherapy for extensive-stage small cell lung cancer experienced a treatment-related myelosuppressive episode, results of a retrospective study published in Cancer Medicine showed.
Escape room adds ‘fun and engaging’ element to orientation for cancer infusion nurses
During the time that nurse educator Lauren McGovern, MSN, RN, OCN, researched ways to gamify oncology infusion nursing orientation, she also happened to be looking for an escape room to entertain her kids.
Cemiplimab plus chemotherapy improves quality of life for patients with advanced NSCLC
The addition of cemiplimab to chemotherapy significantly improved pain symptoms and delayed time to definitive clinically meaningful deterioration of disease symptoms and functions among patients with advanced non-small cell lung cancer.
Disulfiram and copper ‘should not be recommended’ for patients with recurrent glioblastoma
The addition of disulfiram and copper to chemotherapy did not result in a significant survival benefit for patients with recurrent glioblastoma, according to data published in JAMA Network Open.
Mirvetuximab soravtansine-gynx extends survival for certain women with ovarian cancer
Mirvetuximab soravtansine-gynx conferred a 33% reduction in risk for death compared with chemotherapy for women with folate receptor alpha-positive platinum-resistant ovarian cancer, according to topline data from the agent’s manufacturer.
Novel ultrasound device helps chemotherapy cross blood-brain barrier
The use of low-intensity pulsed ultrasound with concomitant administration of IV microbubbles can improve the delivery of albumin-bound paclitaxel and carboplatin through the blood-brain barrier, study results showed.
Prehabilitation during neoadjuvant chemotherapy benefits patients with breast cancer
Prehabilitation during neoadjuvant chemotherapy appeared feasible and well received among a small cohort of women with breast cancer, according to results of a pilot study.
Addition of immunotherapy to chemotherapy improves survival rates of infants with leukemia
The addition of blinatumomab to Interfant-06 chemotherapy appeared safe for infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia, according to data published in The New England Journal of Medicine.
Perioperative toripalimab regimen extends EFS in resectable stage III NSCLC
A combination of toripalimab and perioperative chemotherapy significantly extended EFS compared with chemotherapy alone among patients with resectable stage III non-small cell lung cancer, according to results of a randomized phase 3 study.