Chemotherapy

DESTIN, Fla. — Stem cell transplantation, accompanied by total body radiation, is the only “cure” for progressive systemic sclerosis currently available, according to a speaker at the Congress of Clinical Rheumatology East annual meeting.

The addition of pembrolizumab to chemotherapy as adjuvant therapy did not confer significant improvement in DFS compared with placebo in women with newly diagnosed, high-risk endometrial cancer.

Researchers at Brigham and Women’s Hospital developed a tool that predicts risks for moderate to severe kidney injury after treatment with the chemotherapy drug cisplatin.

Palliative care significantly improved quality of life among patients hospitalized for bone marrow transplant, according to results of a multicenter randomized trial.

A regimen of pembrolizumab plus trastuzumab and chemotherapy extended OS for individuals with HER2-positive locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma.

A multi-institutional team of researchers created a statistical model capable of predicting the risk for premature menopause among women who survived childhood cancer.

New guidelines for vaccinating adults with solid or hematologic cancers detailed the importance of vaccination optimization, multidisciplinary coordination and vaccination of household members.

Compared with standard-of-care chemotherapy, trastuzumab deruxtecan demonstrated a statistically significant improvement in PFS among certain patients with metastatic breast cancer, according to a press release from the manufacturer.

Exagamglogene autotemcel gave most patients with beta-thalassemia transfusion independence and drastically reduced the number of vaso-occlusive crises in those with sickle cell disease in a pair of phase 3 trials.

Researchers at Columbia University's Herbert Irving Comprehensive Cancer Center are investigating a lung cancer treatment that can be delivered directly to the lungs.