Cervical Intraepithelial Neoplasia
Cervical precancer incidence falls 80% among women most likely to be vaccinated for HPV
From 2008 to 2022, the incidence of cervical precancers fell by 80% among screened women aged 20 to 24 years, supporting recommendations for HPV vaccination at ages 11 to 12 years, researchers wrote in Morbidity and Mortality Weekly Report.
Cervical dysplasia incidence decreased over 14 years for women younger than 25 years
From 2007 to 2020, the incidence of cervical intraepithelial neoplasia grades 1, 2 and 3 continuously decreased among women aged 15 to 25 years while increasing among women aged 25 to 29 years, researchers reported.
Data show longer intervals between HPV testing likely safe
A 5-year interval between cervical cancer screenings using HPV testing does not increase risk for cervical precancer detection compared with cytology every 3 years and may be a more effective screening method long term, researchers report.
Actively monitoring cervical lesions increases long-term cervical cancer risk
Women who underwent active surveillance for cervical intraepithelial neoplasia grade 2 had an increased long-term risk for cervical cancer compared with women who received immediate treatment, according to findings published in The BMJ.
Immunomodulators heighten risk for high-grade cervical neoplasia, cancer in women with IBD
Cumulative exposure to immunomodulators increased the risk for high-grade cervical intraepithelial neoplasia and cervical cancer in women with inflammatory bowel disease, according to data from Alimentary Pharmacology & Therapeutics.
HPV vaccination does not mean lower risk for cervical intraepithelial neoplasia
A history of HPV vaccination may not reliably help physicians triage women for less intensive management after an abnormal cervical screening test result, according to researchers.
Risk for injuries increases during diagnostic workup of cervical cancer
Women with invasive cervical cancer demonstrated increased risks for iatrogenic and noniatrogenic injuries during diagnostic workup, according to results of a study published in Cancer Epidemiology, Biomarkers & Prevention.
Just one dose of HPV vaccine may confer durable cervical cancer protection
One dose of the HPV vaccine appeared to be as effective as multiple doses in preventing preinvasive cervical disease among adolescents vaccinated between ages 15 and 19 years, according to results of a retrospective study published in Cancer.
Mailed HPV tests increase cervical cancer screening
Mailing HPV testing kits to women who were overdue for recommended Pap testing led to 50% more cervical cancer screenings but they did not increase the detection of cervical precancer, according to study results published in JAMA Network Open.