Ceftriaxone
Ceftriaxone lessens early ventilator-associated pneumonia in patients with brain injury
One dose of ceftriaxone lowered the risk for ventilator-associated pneumonia within the first week of mechanical ventilation among patients with acute brain injury, according to results published in The Lancet Respiratory Medicine.
Routine lab monitoring for cefazolin, ceftriaxone in OPAT may be ‘excessive’
Few adverse events following outpatient parenteral antimicrobial therapy containing cefazolin and ceftriaxone were identified using routine laboratory monitoring, leading researchers to say the practice may be “excessive.”
Ertapenem noninferior to ceftriaxone in treating gonorrhea, study finds
A trial that evaluated three alternative treatments for anogenital gonorrhea found that a single dose of ertapenem was 99% effective — on par with ceftriaxone, which is recommended as first-line therapy.
High-dose ceftriaxone noninferior to dual therapy for extragenital gonorrhea in MSM
High-dose ceftriaxone monotherapy is as effective as dual therapy for the treatment of extragenital Neisseria gonorrhoeae among men who have sex with men, study results from Japan showed.
In update, CDC recommends ceftriaxone alone for uncomplicated gonorrhea
Leptospirosis: A challenging diagnosis
Leptospirosis is a bacterial infection produced by spirochetes in the genus Leptospira. Leptospira are aerobic but are difficult to cultivate and take many days to grow. They stain poorly with Gram’s stain and are best visualized with silver stain, dark field microscopy or fluorescent microscopy.
Entasis enrolls first patient in phase 3 trial of gonorrhea treatment
WASHINGTON — Entasis Therapeutics announced at the World Anti-Microbial Resistance Congress that it has enrolled the first patient in a global phase 3 trial of oral zoliflodacin for the treatment of uncomplicated gonorrhea.
Most physicians lack on-site antimicrobials for treating gonorrhea and syphilis
Despite the trending rise in STDs in the United States, new data published in Emerging Infectious Diseases showed that most physicians do not have injectable antimicrobial drugs available on-site to treat gonorrhea and syphilis.
Antibiotic-free or organic poultry half as likely to contain MDR Salmonella
WASHINGTON — Multidrug-resistant Salmonella was detected twice as often in samples of meat from conventionally-raised chicken and turkeys compared with antibiotic-free or organic poultry, according to findings from a study conducted in Pennsylvania.
Novel drug combination noninferior to meropenem for treating cUTIs
A novel combination that includes ceftriaxone, sulbactam and disodium EDTA, or CSE, was noninferior to meropenem for the treatment of complicated UTIs, or cUTIs, caused by extended-spectrum beta-lactamase-producing, or ESBL-producing, gram-negative bacteria, according to results from the phase 3 PLEA trial.