Cefazolin

Healio spoke with experts about how the new administration could affect a range of important health issues, including vaccines, nutrition, chronic conditions, insurance and reproductive health care.

A higher cefazolin dose was not associated with decreased rates of surgical site infections among obese patients undergoing elective colorectal surgery, study data showed.

Use of a tourniquet may reduce local tissue concentrations of cefazolin, which could increase the risk of periprosthetic joint infection for patients undergoing total knee arthroplasty, according to published data.

Few adverse events following outpatient parenteral antimicrobial therapy containing cefazolin and ceftriaxone were identified using routine laboratory monitoring, leading researchers to say the practice may be “excessive.”

Cefazolin reduced surgical site infections compared with second-line antibiotics among patients with a beta-lactam allergy who had total joint arthroplasty, with no increase in hypersensitivity reactions, researchers determined.

None of the patients with a penicillin allergy label who received cefazolin before surgery experienced allergic symptoms related to the antibiotic, according to a study published in Annals of Allergy, Asthma & Immunology.

Antibiotic stewardship may increase preferred prophylaxis and cefazolin use in patients with non-severe penicillin allergies who undergo total joint arthroplasty, according to recently presented results.

Published results showed no statistically significant differences in the rate of surgical site infections after foot and ankle trauma surgery with use of 1g or 2g of cefazolin.