Catastrophic Antiphospholipid Syndrome

About half of the patients with catastrophic antiphospholipid syndrome have cutaneous involvement, which can help predict outcomes in this condition, according to a study.

ORLANDO — Patients with catastrophic antiphospholipid syndrome appeared to have high rates of mutations in complement regulatory genes that could lead to uncontrolled complement activation and a more severe phenotype, according to study results presented during the plenary session of ASH Annual Meeting and Exposition.