Cardiovascular Disease

Although it was thought that drug overdoses and deaths may be the reason for stalled increase in U.S. life expectancy, a stall in the decline of CV deaths may be the more likely reason, according to a study published in the Proceedings of the National Academy of Sciences.

The underlying etiology of the metabolic syndrome, a cardiometabolic risk factor cluster — central obesity, low HDL cholesterol, impaired glucose tolerance, elevated triglycerides and hypertension — remains the subject of debate. Gerald Reaven, MD, the Stanford University researcher who coined the syndrome’s original name of “syndrome X,” suggested insulin resistance was the cause, but this is only partly correct. Insulin resistance is just one of the outcomes of circadian dysfunction, along with the above risk factors.

Transgender women have modified profiles of biomarkers that correlate with with systemic inflammation and cardiovascular disease that are seemingly affected by feminizing hormonal therapy and HIV, according to findings from CROI.

Researchers recently reported that adults who skip breakfast are more likely to develop CVD and are at greater risk for mortality compared to those who never skip the meal — one of the top stories in endocrinology last week.

SCOTTSDALE, Ariz. —Rheumatologists, focused as they are on inflammatory symptoms, are often less familiar with cardiovascular management, according to M. Elaine Husni, MD, MPH, of the Cleveland Clinic.

The FDA on Monday issued a new draft guidance that no longer includes a recommendation that drug companies conduct cardiovascular outcomes trials demonstrating safety for all type 2 diabetes drugs, according to an agency press release.

Women aged 45 years or younger who undergo bilateral oophorectomy and report having a first-degree relative who experienced premature myocardial infarction are at greater risk for cardiovascular death or death from any cause when compared with women without either condition, according to findings published in Menopause.

Women in early menopause who received oral estradiol treatment had a reduced progression of lipid deposition in the carotid arterial wall compared with placebo, according to a secondary analysis of the ELITE trial presented at the American Heart Association Epidemiology, Prevention, Lifestyle and Cardiometabolic Health Scientific Sessions.

Adults who skip breakfast are more likely to develop cardiovascular disease and have greater rates of all-cause mortality than those who typically eat a morning meal, according to findings published in Clinical Nutrition.

Compared with men, women had increased flow and cardiac strain parameters associated with left ventricular mass, according to a study published in Radiology: Cardiothoracic Imaging.