Cardiotoxicity

ATLANTA — Enalapril plus standard care was not superior to standard care alone for preventing cardiotoxicity in patients receiving treatment for breast cancer or lymphoma, according to new data from the PROACT trial.

A miniature, three-dimensional heart model, called the “heart-on-a-chip,” successfully used reprogrammed stem cells to determine cardiotoxicity of cancer drugs on the human heart, according to a study published in Lab on a Chip.

Delix Therapeutics announced it has received a $320,000 grant from NIH’s National Institute on Drug Abuse to advance its novel, non-hallucinogenic neuroplastogen for treatment of substance use disorders, including opioid and stimulant use.

A small study showed no impact from troponin-guided carvedilol and candesartan intervention to preserve cardiac function among seemingly high-risk patients undergoing chemotherapy.

Breast Cancer Awareness Month is observed every October.

Overweight/obesity was independently prognostic of chemotherapy-related cardiotoxicity among patients undergoing treatment for breast cancer, according to a small study.

Toxic metals such as lead, cadmium and arsenic found in food and water represent a significant hazard CV health in the U.S., particularly among historically underrepresented communities, according to a scientific statement.

Adolescent and young adult cancer survivors who received cardiotoxic treatments exhibited a high burden of poor cardiac function, according to study results presented at American Association for Cancer Research Annual Meeting.

In this edition, elevated cardiotoxicity risk for Black patients after chemotherapy; CV risk factor disparities in childhood cancer survivors; neural network helps identify potential targets for cancer drugs and more.

Results of a large meta-analysis indicated that Black race was associated with greater odds of cardiotoxicity and HF diagnosis after chemotherapy compared with white and non-Black race, a speaker reported.