Cardiac Output
Patients with PAH show more benefit with seralutinib if deemed responders
Among patients with pulmonary arterial hypertension treated with 72-week seralutinib, those deemed responders had more improved measures, according to a poster presented at the Pulmonary Vascular Research Institute 2025 Annual Congress.
Younger age at heart failure diagnosis tied to dementia risk
Adults diagnosed with HF before age 65 years were 67% more likely to be diagnosed with dementia during 12 years of follow-up compared with adults diagnosed at age 75 years or older, suggesting careful neurocognitive monitoring is needed.
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Bainbridge Reflex
The Bainbridge reflex (aka, atrial reflex) occurs when the heart rate increases in response to a rise in atrial pressure.
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Chronic Heart Failure - Heart Failure with Preserved Ejection Fraction Topic Review
Chronic heart failure occurs when either the left ventricle, the right ventricle, or both require elevated filling pressures to maintain cardiac output. Heart failure is a syndrome, not a specific disease, and occurs as a final common pathway in multiple disease states.
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Cardiorenal Syndrome
The cardiorenal syndrome occurs when low cardiac output results in decreased renal perfusion and renal failure. The treatment is aimed at increasing cardiac output frequently by using cardiac inotropes such as dobutamine and milrinone.
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Cardiac Output
Cardiac output is the overall amount of blood flow that the heart pumps forward. The standard unit to express the cardiac mL/min or cc/min.
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Cardiogenic Shock
Cardiogenic shock occurs when the heart is not able to pump enough blood to generate adequate cardiac output to maintain normal blood pressure.
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Aortic Regurgitation - Symptoms
The symptoms of aortic valve regurgitation are those predominately of congestive heart failure. As chronic aortic regurgitation develops slowly over time, the left ventricle can easily compensate slowly as described previously.
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Congestive heart failure - systolic
Activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) occur in patients with systolic heart failure.