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Carcinoma

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August 23, 2023
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Survival in Merkel cell carcinoma may improve with Mohs vs. wide local excision

Survival in Merkel cell carcinoma may improve with Mohs vs. wide local excision

Patients with Merkel cell carcinoma may have better survival outcomes when treated with Mohs micrographic surgery compared with wide local excision, according to a study.

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August 14, 2023
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Novel nonsurgical immunotherapy treatment shows promise in basal cell carcinoma

Novel nonsurgical immunotherapy treatment shows promise in basal cell carcinoma

Verrica Pharmaceuticals Inc. has reported lesion clearance data from part one of an ongoing phase 2 study of VP-315 for the treatment of basal cell carcinoma, according to a press release from Verrica’s licensing partner, Lytix Biopharma.

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July 13, 2023
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Optical coherence tomography improves basal cell carcinoma detection after topicals

Optical coherence tomography improves basal cell carcinoma detection after topicals

When used in tandem with clinical and dermoscopic examination, optical coherence tomography significantly improved the ability to detect recurrent or residual basal cell carcinomas after topical treatment, according to a study.

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May 18, 2023
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Metvix yields positive cosmetic results in basal cell carcinoma treatment

Metvix yields positive cosmetic results in basal cell carcinoma treatment

Topical photodynamic therapy and methyl aminolevulinate, marketed as Metvix, displayed effectiveness and good cosmetic outcomes in the treatment of basal cell carcinomas following surgery, according to a study.

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May 09, 2023
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Patients with Merkel cell carcinoma see similar survival with wide local excision, Mohs

Patients with Merkel cell carcinoma see similar survival with wide local excision, Mohs

Wide local excision and Mohs micrographic surgery exhibited no difference in survival outcomes among patients with Merkel cell carcinoma, according to a study.

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March 07, 2023
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Lack of consensus among Mohs surgeons diagnosing in situ carcinoma

Lack of consensus among Mohs surgeons diagnosing in situ carcinoma

While most Mohs surgeons agree on diagnostic differentiations between actinic keratosis and squamous cell carcinoma in situ, variability exists in the interpretation of in situ carcinoma on histological frozen sections, according to a study.

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February 28, 2023
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Need for consensus in diagnostic practices for actinic keratoses, squamous cell carcinoma

Need for consensus in diagnostic practices for actinic keratoses, squamous cell carcinoma

Due to the lack of clarity in literature, widespread implementation of consensus recommendations for actinic keratoses and cutaneous squamous cell carcinoma is needed, according to a study.

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February 03, 2023
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Pembrolizumab regimen extends PFS in advanced, recurrent endometrial carcinoma

Pembrolizumab regimen extends PFS in advanced, recurrent endometrial carcinoma

The addition of pembrolizumab to chemotherapy significantly extended PFS as first-line treatment for advanced or recurrent endometrial carcinoma, according to the agent’s manufacturer.

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November 23, 2022
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Robotic liver resection safe, effective for hepatocellular carcinoma

Robotic liver resection safe, effective for hepatocellular carcinoma

Robotic liver dissection appeared safe and effective compared with open liver resection among patients with hepatocellular carcinoma, according to study results published in JAMA Surgery.

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August 09, 2022
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Phase 3 trial of tislelizumab in hepatocellular carcinoma meets survival endpoint

A phase 3 trial of the PD-1 inhibitor tislelizumab met its primary endpoint of noninferior OS compared with sorafenib as first-line treatment for adults with unresectable hepatocellular carcinoma, according to the agent’s manufacturer.

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