Carbapenem
Threat of antimicrobial resistance on the rise in low-, middle-income countries
New estimates presented at ESCMID Global Congress show that antimicrobial resistance prevalence in WHO gram-negative priority pathogens may be “substantial” in countries lacking current data.
Carbapenem-sparing cUTI treatment shows superiority to piperacillin-tazobactam
Cefepime-enmetazobactam demonstrated superiority compared with piperacillin-tazobactam in a phase 3 trial involving more than 1,000 adults with complicated UTIs and acute pyelonephritis, according to results presented at IDWeek.
Use of high-risk antibiotics correlates with more hospital-associated CDI
Using high-risk antibiotics is an independent predictor of hospital-associated Clostridioides difficile infections, or HA CDIs, according to a study published in Infection Control & Hospital Epidemiology.
Core stewardship intervention feasible at community hospitals
Researchers tested two core Infectious Diseases Society of America-recommended antimicrobial stewardship interventions at four community hospitals in North Carolina and found that one — post-prescription audit and review by a pharmacist after 72 hours of therapy — was feasible in facilities with limited resources and little to no antimicrobial stewardship expertise.