Cancer

The novel PARP inhibitor BMN 673 improved response in patients with BRCA-related breast and ovarian cancers, according to study results presented at the International Conference on Molecular Targets and Cancer Therapeutics.

Suppression of the phosphorylation of the protein S6 after the initiation of RAF inhibitor therapy may serve as a functional biomarker to guide the treatment of patients with BRAF-mutant melanoma, according to study results presented at the International Conference on Molecular Targets and Cancer Therapeutics.

The antibody-drug conjugate MLN0264 demonstrated antitumor activity in pancreatic cancer xenograft models, according to study results presented at the International Conference on Molecular Targets and Cancer Therapeutics.

A new molecular diagnostic prototype platform detected BRAF mutations in cancer tissue samples faster and more accurately vs. Clinical Laboratory Improvement Amendments-approved lab results, according to findings presented at the International Conference on Molecular Targets and Cancer Therapeutics.

I have written previously about the ability of Twitter to facilitate conversations around topics relevant to hematology and oncology.

The novel agent dinaciclib demonstrated activity in xenographic models against the RAS pathway of the KRAS mutation associated with pancreatic cancer, according to study results presented at the International Congress on Molecular Targets and Cancer Therapeutics.

CRLX101 combined with antiangiogenic therapy inhibited the upregulation of hypoxia-inducible factor 1 alpha, according to findings presented at the International Conference on Molecular Targets and Cancer Therapeutics.

A new two-stage ovarian cancer screening strategy that incorporates a carbohydrate antigen 125 blood test and Risk of Ovarian Cancer Algorithm calculation achieved high specificity with few false-positive results in a cohort of postmenopausal women, according to results of an 11-year study.

Delirium is common in hospitalized patients with advanced cancer and many factors contribute to its cause, according to findings of a retrospective study.