Cancer

This year, researchers found that of patients with high-risk, early-stage ovarian cancer, 72% had one or more symptoms and 28% were asymptomatic.

A new clinical practice guideline from the Endocrine Society recommends treatment with IV bisphosphonates or denosumab in addition to adequate hydration for adults with moderate hypercalcemia of malignancy.

mRNA-4157/V940, an investigational personalized mRNA cancer vaccine, with Keytruda met the primary endpoint of recurrence-free survival in a phase 2b trial for the adjuvant treatment of stage III/IV melanoma after surgical resection.

Implementation of lung cancer screening across five diverse health care systems led to higher rates of stage I diagnoses and lower rates of stage IV disease, study results showed.

Spaceflight may place astronauts at increased risk for developing mutations that can lead to cancer and heart disease, according to a study published in Nature Communications Biology.

Certain sociodemographic and modifiable risk factors appeared associated with higher risk for cardiovascular disease among adolescent and young adult cancer survivors, according to research published in Cancer.

PHILADELPHIA — Patients with rheumatic diseases and previous malignancy do not demonstrate a higher cancer risk with TNF inhibitors vs. other biologic and targeted synthetic DMARDs, according to data presented at ACR Convergence 2022.

Patients with nasopharyngeal cancer who underwent COVID-19 vaccination had a better response to a combination of anti-PD-1 therapy and chemotherapy than their unvaccinated counterparts, according to a letter published in Annals of Oncology.

Higher allostatic load, a measure of lifelong stress, correlated with increased risk for cancer mortality, especially among younger populations, according to study results published in SSM Population Health.

A combination of dostarlimab-gxly and standard-of-care chemotherapy significantly extended PFS compared with placebo and chemotherapy among women with primary advanced or recurrent endometrial cancer, topline data showed.