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Cancer Therapy

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March 12, 2025
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Early adverse effects from prostate cancer therapy predict long-term complications

Early adverse effects from prostate cancer therapy predict long-term complications

Men who experience acute adverse effects after radiation therapy for prostate cancer may be at higher risk for more serious long-term urinary and bowel complications, according to results of a meta-analysis published in Lancet Oncology.

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February 28, 2025
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With community oncology ‘at risk’, alliance outlines prescription for health care reform

With community oncology ‘at risk’, alliance outlines prescription for health care reform

Debra Patt, MD, PhD, MBA, FASCO, has often found her career has placed her at the intersection of public policy and clinical informatics.

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February 27, 2025
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VIDEO: Trial builds on current microsatellite instability-high colorectal cancer therapy

VIDEO: Trial builds on current microsatellite instability-high colorectal cancer therapy

In this video, Arvind N. Dasari, MD, MS, discussed the results of the CheckMate 8HW trial in which nivolumab and ipilimumab were compared with nivolumab monotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer.

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February 25, 2025
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Novel amifostine delivery could be ‘tremendous advance’ for pancreatic cancer therapy

Novel amifostine delivery could be ‘tremendous advance’ for pancreatic cancer therapy

Fear of nuclear fallout has led to a novel therapeutic approach that could significantly extend the lives of individuals with pancreatic cancer or other gastrointestinal malignancies.

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February 19, 2025
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Cancer therapy may impair cardiorespiratory fitness for years after treatment

Cancer therapy may impair cardiorespiratory fitness for years after treatment

Cancer treatment, primarily chemotherapy, is associated with impaired cardiorespiratory fitness years after treatment has ended and regardless of cancer subtype, according to a meta-analysis published in JACC: CardioOncology.

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February 18, 2025
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Statins may enhance effectiveness of immune checkpoint inhibitors

Statins may enhance effectiveness of immune checkpoint inhibitors

Concomitant use of statins improved survival among people with cancer treated with immune checkpoint inhibitors, according to results of a meta-analysis.

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January 31, 2025
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Osimertinib linked to more therapy-related cardiac events than other TKIs for NSCLC

Osimertinib linked to more therapy-related cardiac events than other TKIs for NSCLC

Patients with EGFR-mutated non-small cell lung cancer treated with osimertinib experienced more cancer therapy-related cardiac events than those treated with other EGFR tyrosine kinase inhibitors.

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January 24, 2025
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‘Potential gamechanger’: Researchers discover basis for immunotherapy-induced myocarditis

‘Potential gamechanger’: Researchers discover basis for immunotherapy-induced myocarditis

Clinicians may one day be able to treat immune checkpoint inhibitor-related myocarditis without disrupting cancer therapy, findings from a cellular investigation showed.

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January 23, 2025
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Glucarpidase improves recovery after chemotherapy-induced kidney toxicity

Glucarpidase improves recovery after chemotherapy-induced kidney toxicity

Glucarpidase significantly improved kidney function for patients who developed acute kidney injury from high-dose methotrexate, according to results of a large, multicenter observational study.

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January 14, 2025
5 min read
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‘More rigorous’ discussion needed about potential complications after prostate cancer therapy

‘More rigorous’ discussion needed about potential complications after prostate cancer therapy

Men treated with radiotherapy and prostatectomy for prostate cancer exhibit significantly higher risk for numerous urinary and sexual complications compared with the general population, according to results of a cohort study.

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