Cambridge University

Researchers have developed an algorithm tailored to age that can predict the risk for incident metabolic syndrome among young people with psychosis, according to study results published in The Lancet Psychiatry.

Avacopan is superior to prednisone taper in preventing relapse in patients with antineutrophil cytoplasmic antibody-associated vasculitis at 1 year, and is at least as effective as steroids in controlling the disease at 6 months, according to data.

Certain genetic mutations in breast cancer predisposition genes could inform screening and improve management of women at low risk for the disease, according to results of two studies published in The New England Journal of Medicine.

Patients acquired myeloproliferative neoplasm driver mutations early in life, often in utero, which then expanded at variable rates over their lifetime before diagnosis, according to study results.

Random plasma glucose tests at 12 weeks’ gestation and fasting plasma glucose or HbA1c at 28 weeks’ gestation can safely identify women with hyperglycemia at risk for suboptimal pregnancy outcomes during COVID-19, study data show.

Genetic modifiers — many discovered in the late 1990s — can be “harnessed” to better understand the processes and mechanisms behind weight gain and one day even regulate appetite, according to a speaker.

Studies of genetic causes of severe obesity — and resistance to obesity — can help identify mechanisms of weight regulation and suggest targets for obesity therapies, according to a speaker at ObesityWeek Interactive.

Women younger than 50 years with polycystic ovary syndrome were at elevated risk for CVD compared with younger women without it, according to a research letter published in the European Journal of Preventive Cardiology.

Rituximab, used alongside glucocorticoids, is highly efficacious in re-inducing remission among relapsed patients with ANCA-associated vasculitis, according data published in Annals of the Rheumatic Diseases.