Budesonide

A fixed-dose combination of albuterol and budesonide at 180/160 µg and 180/80 µg demonstrated significant benefits in patients with asthma, according to high-level results from the MANDALA and DENALI phase 3 trials.

New data from the phase 3 TYREE study demonstrate efficacy of a fixed-dose combination of budesonide and albuterol in a single pressurized metered-dose inhaler to prevent exercise-induced bronchoconstriction in individuals with asthma.

In patients with eosinophilic esophagitis, budesonide oral suspension improved histologic, symptomatic and endoscopic outcomes, according to research published in Clinical Gastroenterology and Hepatology.

Twice-daily budesonide oral suspension, or BOS, improved outcomes in pediatric patients with eosinophilic esophagitis, according to research presented at this year’s virtual American Academy of Allergy, Asthma and Immunology Annual Meeting.

Takeda Pharmaceutical announced the FDA accepted its new drug application and granted priority review fo r TAK-721, an investigational therapy budesonide oral suspension intended for the treatment of eosinophilic esophagitis.

Recent data showed that topical budesonide may be linked to a decrease in endoscopic strictures after endoscopic mucosal resection or endoscopic submucosal dissection.

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The FDA has approved triple inhaled therapy for maintenance treatment of patients with COPD, according to a press release from AstraZeneca.

Triple inhaled therapy with twice-daily budesonide, at two doses, glycopyrrolate and formoterol reduced the rate of moderate or severe COPD exacerbations compared with two dual-combination therapies, according to data from the ETHOS trial.

This year’s CHEST Annual Meeting, held from Oct. 19 to 23 in New Orleans, highlighted important research and issues in pulmonary, critical care and sleep medicine.