Bronchodilator

Inhaled dual bronchodilator therapy did not decrease respiratory symptoms among individuals who were current or former smokers and had respiratory symptoms but preserved lung function without COPD, according to results of the RETHINC study.

Patients with COPD and a history of asthma had a higher prevalence of elevated fractional exhaled nitric oxide levels compared with patients with COPD and no asthma history, according to new data published in Thorax.

A recent meta-analysis published in JAMA Pediatrics suggests that nebulized normal saline may be considered an active treatment as opposed to a placebo in studies evaluating therapies for acute viral bronchiolitis in young children.

NEW ORLEANS — In a post hoc analysis of pooled data from four phase 3 studies, combination therapy with tiotropium plus olodaterol resulted in greater improvements in lung function and symptoms than with tiotropium alone in patients with COPD who were not using inhaled corticosteroids.

NEW ORLEANS — In a post hoc analysis of the LIBERTY ASTHMA VENTURE study, treatment with dupilumab resulted in reduced severe asthma exacerbations in patients with oral corticosteroid-dependent severe asthma both with and without early improvements in lung function.

NEW ORLEANS — In a post hoc analysis of the LIBERTY ASTHMA QUEST study, treatment with dupilumab reduced severe exacerbations and improved lung function regardless of early or late onset of asthma.

NEW ORLEANS — In a subgroup analysis of the ASCENT-COPD trial, treatment with the long-acting antimuscarinic bronchodilator aclidinium bromide reduced the risk for new exacerbations compared with placebo in patients with moderate to very severe COPD and high cardiovascular risk, regardless of prior exacerbations.

NEW ORLEANS — Use of spirometry with bronchodilator testing can help reduce overdiagnosis of COPD as well as help differentiate COPD from asthma and asthma-COPD overlap syndrome, researchers reported at the CHEST Annual Meeting.

Healio Pulmonology has you covered. The Editors have compiled a list of the most-popular articles posted on Healio Pulmonology in July.