Bronchiectasis

Adults with bronchiectasis and a Pseudomonas aeruginosa infection had lower bacterial density and better quality of life when treated with tobramycin inhalation solution, according to study results published in CHEST.

Children with bronchiectasis taking azithromycin had the greatest benefits from weeks 17 to 62 out of 105 weeks of treatment, according to study results published in CHEST.

Photon-counting detector CT found more subtle lung abnormalities that may indicate irreversible lung fibrosis in symptomatic patients following COVID-19 infection than conventional CT, according to a study published in Radiology.

Combining manuka honey and the antibiotic amikacin in a lab-based nebulization formulation was effective for inhibiting Mycobacterium abscessus and drug-resistant clinical isolates in patients with cystic fibrosis or bronchiectasis.

The loss of small, distal pulmonary arteries was associated with progression of CT-derived bronchiectasis, especially among smokers with COPD, according to results published in Respiratory Medicine Journal.

Daily tiotropium via the HandiHaler device improved lung function but did not reduce frequency of exacerbations over 6 months in patients with stable bronchiectasis, according to results published in European Respiratory Journal.

The Healio Editors compiled the most-read news in pulmonology posted in April.

The FDA granted breakthrough therapy designation to colistimethate sodium powder for nebulization solution to reduce pulmonary exacerbations in adults with non-cystic fibrosis bronchiectasis and Pseudomonas aeruginosa.

In a new study published in Chest, cardiovascular events occurred in 30% of patients with bronchiectasis after an acute exacerbation.

Small airways loss appears to be an important aspect in the pathophysiology of fibrotic pulmonary sarcoidosis, researchers concluded in a new Chest study.