Braf V600 Mutant Metastatic Melanoma

Circulating tumor DNA measurements before and during treatment could help guide selection of therapy for patients with BRAF V600-mutant unresectable or metastatic melanoma, according to study results published in The Lancet Oncology.

The addition of spartalizumab to dabrafenib and trametinib failed to prolong PFS among patients with BRAF-mutated advanced melanoma, according to results from the randomized phase 3 COMBI-i trial presented at ESMO Virtual Congress 2020.

The past decade has ushered in major transformations in the prevention, diagnosis and treatment of melanoma.