Bone Mineral Density

Researchers said that a new study examining the impact of oral anticoagulants on bone health underscores the importance of assessing patients who are taking these medications for bone mineral density and quality.

Adults prescribed any oral anticoagulation therapy have lower bone mineral density and trabecular bone score compared with controls, with a stronger negative effect observed among those prescribed warfarin, data published in Bone show.

An above average birth weight is associated with lower bone mineral density and higher fracture risk later in life, according to data published in the Journal of Bone and Mineral Research.

Young women with obesity have a higher areal bone mineral density, better hip structure and higher volumetric BMD in all femoral compartments compared with women with normal weight, according to a study published in Bone.

Evaluating bone mineral density can help predict atherosclerotic CVD events in women, according to a study published in Heart.

Older men with higher bone mineral density and preserved cortical bone are less likely to experience a major adverse coronary event, according to a study published in the Journal of Bone and Mineral Research.

Founder of India’s first bone density and osteoporosis service, Ambrish Mithal, MD, DM, played a key role in establishing osteoporosis as a serious national health problem.

Following short-term therapy with teriparatide plus denosumab with a single dose of zoledronic acid may prevent bone loss associated with denosumab cessation among postmenopausal women, according to a study published in the Journal of Bone and Mineral Research.

The experience with fluoride made clear that increased BMD does not result in reduced fractures when the mineralization of bone is compromised. Therefore, good data on bone histology is a prerequisite for accepting BMD as a surrogate for fracture. Strontium increases BMD substantially, but this is significantly contributed to by the heavier strontium atoms replacing calcium in bone mineral. Thus, the increase in BMD does not reflect an increase in bone tissue volume, again dissociating BMD from bone strength.

Osteoporotic fractures represent a costly human and socioeconomic burden. Even with currently available drugs, treatments that more effectively increase bone mineral density, reduce fractures and reverse the disease are needed.