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February 06, 2025
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Central obesity metrics more accurate than BMI in estimating excess weight-related CRC

Central obesity metrics more accurate than BMI in estimating excess weight-related CRC

Central obesity measures of waist circumference and waist-to-hip ratio appear to be more accurate and consistent indicators of colorectal cancer incidence compared with BMI, according to a study published in JAMA Network Open.

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February 04, 2025
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Weight cycling may worsen kidney function for adults with type 1 diabetes

Weight cycling may worsen kidney function for adults with type 1 diabetes

Adults with type 1 diabetes who partake in weight cycling and repeatedly lose and regain body weight are more likely to develop diabetic kidney disease, researchers reported in The Journal of Clinical Endocrinology & Metabolism.

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December 23, 2024
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Adults with obesity lost 22.7% of body weight with combination GLP-1/amylin analog

Adults with obesity lost 22.7% of body weight with combination GLP-1/amylin analog

A combination GLP-1/amylin analog conferred a superior reduction in body weight at 68 weeks vs. placebo for adults with obesity or overweight with at least one weight-related comorbidity, according to top-line results from a phase 3 trial.

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November 21, 2024
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ESSENCE: Semaglutide bests placebo in MASH resolution, fibrosis improvement at 72 weeks

ESSENCE: Semaglutide bests placebo in MASH resolution, fibrosis improvement at 72 weeks

SAN DIEGO — Semaglutide was superior to placebo in metabolic dysfunction-associated steatohepatitis resolution and improvement in fibrosis at 72 weeks, with a safety profile consistent with previous studies, according to late-breaking data.

Clinical Guidance
Measles
Assessment and Treatment

Post-Exposure Prophylaxis (PEP)

Gary S. Marshall, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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October 17, 2024
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OSA risk in middle age linked to early childhood, adulthood BMI, weight gain

OSA risk in middle age linked to early childhood, adulthood BMI, weight gain

BOSTON — Adults who experienced BMI or weight gains between age 2 years and 5 years, as well as after age 11 years, faced increased odds for high obstructive sleep apnea risk, according to data presented at the CHEST Annual Meeting.

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September 19, 2024
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Off-label semaglutide, tirzepatide lower HbA1c and body weight in type 1 diabetes

Off-label semaglutide, tirzepatide lower HbA1c and body weight in type 1 diabetes

Adults with type 1 diabetes using either semaglutide or tirzepatide off-label had greater decreases in body weight and HbA1c than those not treated with either medication, according to a speaker.

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September 16, 2024
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Mazdutide superior to dulaglutide for reducing HbA1c, body weight in type 2 diabetes

Mazdutide superior to dulaglutide for reducing HbA1c, body weight in type 2 diabetes

A once-weekly GLP-1/glucagon dual agonist conferred greater decreases in HbA1c and body weight than the GLP-1 receptor agonist dulaglutide for adults with type 2 diabetes, according to a presenter.

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September 05, 2024
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Greater exposure to PFAS during pregnancy may lead to higher body weight later in life

Greater exposure to PFAS during pregnancy may lead to higher body weight later in life

Exposure to higher amounts of some types of per- and polyfluoroalkyl substances during pregnancy may lead to long-term increases in body weight, waist circumference and fat mass, according to new findings.

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August 08, 2024
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Adults maintain drops in body weight, HbA1c at 1 year after duodenal mucosal resurfacing

Adults maintain drops in body weight, HbA1c at 1 year after duodenal mucosal resurfacing

Adults with obesity and type 2 diabetes had reductions in body weight and HbA1c 1 year after undergoing an endoscopic procedure that resurfaces the duodenum lining, according to top-line results from a real-world registry study.

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