Blood Transfusion

Study findings published in JAMA showed no benefit in using fresh red blood cells — cells stored for a maximum of 7 days — over older red blood cells in critically ill pediatric patients receiving transfusion.

The FDA today approved luspatercept-aamt to treat anemia in adults with beta-thalassemia who undergo regular red blood cell transfusions.

New endoscopic techniques and changes in the pharmacologic landscape prompted an update in guidelines for managing patients with nonvariceal upper GI bleeding.

Patients aged at least 80 years who underwent PCI had an increased risk for in-hospital mortality and morbidity compared with those younger than 80 years, according to a study published in The American Journal of Cardiology.

Administering 20 mL/kg or 30 mL/kg blood transfusions immediately produced similar clinical outcomes over 6 months among African children with severe anemia compared with a triggered strategy, according to results of two randomized trials published in The New England Journal of Medicine.

Pregnancy appeared associated with increased risk for transfusion reactions among women who received blood products, with preeclampsia as the most significant risk factor for complications, according to study results published in Blood Advances.