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January 15, 2025
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FDA clears investigational new drug application for lorundrostat in OSA, hypertension

FDA clears investigational new drug application for lorundrostat in OSA, hypertension

The FDA approved the phase 2 Explore-OSA trial set to assess the highly selective aldosterone synthase inhibitor, lorundrostat, in adults with obstructive sleep apnea and hypertension, according to a press release.

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January 13, 2025
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Maintaining healthy behaviors in early life essential to preserving future heart health

Maintaining healthy behaviors in early life essential to preserving future heart health

Maintaining healthful behaviors may be key to improving the trajectory of heart health from early adolescence into adulthood, according to study findings published in JAMA Cardiology.

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January 09, 2025
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Novel drug confers weight loss of up to 20% at 1 year in phase 2 study

Novel drug confers weight loss of up to 20% at 1 year in phase 2 study

Maridebart cafraglutide, a novel injectable GLP-1 receptor agonist/GIP receptor antagonist, reduced body weight by up to approximately 20% at 1 year in patients with overweight or obesity without a weight loss plateau, according to a presentation.

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January 03, 2025
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Relacorilant improves cardiometabolic metrics for patients with Cushing’s syndrome

Relacorilant improves cardiometabolic metrics for patients with Cushing’s syndrome

Among patients with endogenous hypercortisolism, relacorilant improved cardiometabolic parameters such as blood pressure, HbA1c and weight, according to results of a long-term extension study.

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January 02, 2025
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AAN shares 12 patient-provider conversation starters about brain health

AAN shares 12 patient-provider conversation starters about brain health

In a newly published paper, the American Academy of Neurology promoted 12 key concepts for patients and providers to successfully promote and maintain brain health.

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December 31, 2024
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Caffeine consumption does not significantly impact retinal vascular density

Caffeine consumption does not significantly impact retinal vascular density

While caffeine consumption may elevate blood pressure after 2 hours, it does not have a significant impact on retinal vessel density, according to a study in the Journal of Ophthalmology.

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December 24, 2024
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FDA clears novel at-home BP, pulse rate monitor

FDA clears novel at-home BP, pulse rate monitor

Withings Health Solutions announced its novel cellular BP monitor received FDA clearance to measure BP and pulse rate in adults with arm circumferences of 22 cm to 42 cm or 40 cm to 52 cm.

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December 18, 2024
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Top in endocrinology: Benefits of early response to tirzepatide; fractures in adulthood

Top in endocrinology: Benefits of early response to tirzepatide; fractures in adulthood

A post hoc analysis of the SURMOUNT-1 and SURMOUNT-2 trials found that early responders to tirzepatide, or those who lost at least 5% of body weight by 8 weeks, had greater weight loss and cardiometabolic benefits vs. non-early responders.

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December 17, 2024
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Blood pressure variability linked to impaired cognition in older adults

Blood pressure variability linked to impaired cognition in older adults

In older adults, particularly Black adults, elevated blood pressure variability was associated with lower cognitive score at follow up, according to a study published in Neurology, the medical journal of the American Academy of Neurology.

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December 16, 2024
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Novel GLP-1 analog injection reduced weight for Chinese adults with overweight, obesity

Novel GLP-1 analog injection reduced weight for Chinese adults with overweight, obesity

SAN ANTONIO — For Chinese adults with overweight or obesity, GLP-1 analog injections were safe and well tolerated, demonstrating robust body weight reductions and improved cardiometabolic parameters, researchers reported.

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