Bleeding

SAN DIEGO — Progesterone was not effective at preventing miscarriage or prematurity in patients who presented with first-trimester vaginal bleeding, according to results of the PREEMPT trial.

WASHINGTON — In patients with atrial fibrillation requiring stroke prevention, the novel factor XIa inhibitor asundexian was associated with lower bleeding rates compared with apixaban, according to the results of the PACIFIC-AF trial.

WASHINGTON — Tranexamic acid administered intravenously before and after noncardiac surgery lowered the risk for life-threatening, major and critical organ bleeding compared with placebo, according to results of the POISE-3 trial.

Among patients who underwent transcatheter aortic valve replacement, those with gastrointestinal bleeding were more likely to die in the hospital and had higher costs and longer length of stay, researchers reported.

NASHVILLE, Tenn. — When treating a patient with glaucoma, surgeons should take steps to anticipate and avoid problems related to unwanted blood, according to an expert.

LAA closure (Amplatzer Amulet, Abbott, or Watchman, Boston Scientific) or non-vitamin K antagonist oral anticoagulants in patients with AF.

Milvexian for prevention of venous thromboembolism in patients undergoing total knee arthroplasty.

Head-to-head comparison of two LAA closure devices (Amplatzer Amulet, Abbott, and Watchman FLX or 2.5, Boston Scientific).

Ticagrelor monotherapy after 3 months of dual antiplatelet therapy lowered the incidence of major bleeding events vs. continued DAPT among patients with high bleeding risk who underwent PCI, according to new insights from TWILIGHT.

The Pulmonary Embolism Syncope-Anemia-Renal Dysfunction risk score was successful in estimating risk for early major bleeding in patients with acute pulmonary embolism, according to new research published in Chest.