Bleeding

Compared with those on a higher dose, patients on a lower-dose edoxaban regimen had lower risk for a composite of stroke, major bleeding and death, according to results published in the Journal of the American College of Cardiology.

Among women with atrial fibrillation at elevated CV risk, treatment with high-dose edoxaban vs. warfarin conferred greater reduction in hemorrhagic stroke and major bleeding compared with men, with similar efficacy, researchers reported.

Gingival bleeding may indicate low vitamin C — or ascorbic acid — intake, according to research published in Nutritional Reviews.

Non-vitamin K antagonist oral anticoagulants conferred lower risk for ischemic stroke and major bleeding in patients with atrial fibrillation and a history of gastrointestinal bleeding compared with warfarin, according to study results.

Hemoclipping may be an effective prophylaxis for treatment of large pedunculated polyps, according to a study published in Gastrointestinal Endoscopy.

Single endoscopy was not inferior to second-look endoscopy in decreasing risk for recurrent bleeding in patients with acute upper gastrointestinal bleeding due to peptic ulcer disease, according to study results.

Anticoagulation use or antiplatelet agents were not risk factors for gastrointestinal bleeding in hospitalized COVID-19 patients, according to a study published in Journal of Internal Medicine.

The addition of tranexamic acid prophylaxis to platelet transfusion did not reduce bleeding among patients with blood cancers and severe thrombocytopenia, according to study results presented at the virtual ASH Annual Meeting and Exposition.

Outcomes with 14 days of dual antiplatelet therapy after PCI with a nanocoated stent (Cobra PzF, CeloNova Biosciences) compared with 3- to 6-month DAPT after PCI with a drug-eluting stent.

In this exclusive video from ACG Virtual Annual Meeting, Gabriela Kuftinec, MD MPH, from the department of medicine, division of gastroenterology, University of Miami Leonard M. Miller School of Medicine, discusses the development of a stool color tool that may aid in the diagnosis of gastrointestinal bleeding.